Identity
HGNC
LOCATION
10q24.2
LOCUSID
ALIAS
C10orf65,DHDPS2,DHDPSL,HP3,NPL2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 112817
MIM: 613597
HGNC: 25155
Ensembl: ENSG00000241935
Variants:
dbSNP: 112817
ClinVar: 112817
TCGA: ENSG00000241935
COSMIC: HOGA1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000241935 | ENST00000370642 | H7BY76 |
| ENSG00000241935 | ENST00000370646 | Q86XE5 |
| ENSG00000241935 | ENST00000370647 | Q86XE5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36928260 | 2023 | Kidney cysts in patients with HOGA1 variants. | 0 |
| 37318624 | 2023 | HOGA1 variants in Chinese patients with primary hyperoxaluria type 3: genetic features and genotype-phenotype relationships. | 1 |
| 36928260 | 2023 | Kidney cysts in patients with HOGA1 variants. | 0 |
| 37318624 | 2023 | HOGA1 variants in Chinese patients with primary hyperoxaluria type 3: genetic features and genotype-phenotype relationships. | 1 |
| 34995728 | 2022 | Extended genetic analysis of exome sequencing for primary hyperoxaluria in pediatric urolithiasis patients with hyperoxaluria. | 2 |
| 36259736 | 2022 | HOGA1 gene pathogenic variants in primary hyperoxaluria type III: Spectrum of pathogenic sequence variants, and phenotypic association. | 1 |
| 34995728 | 2022 | Extended genetic analysis of exome sequencing for primary hyperoxaluria in pediatric urolithiasis patients with hyperoxaluria. | 2 |
| 36259736 | 2022 | HOGA1 gene pathogenic variants in primary hyperoxaluria type III: Spectrum of pathogenic sequence variants, and phenotypic association. | 1 |
| 33350326 | 2021 | Mutations in HOGA1 do Not Confer a Dominant Phenotype Manifesting as Kidney Stone Disease. | 1 |
| 33350326 | 2021 | Mutations in HOGA1 do Not Confer a Dominant Phenotype Manifesting as Kidney Stone Disease. | 1 |
| 31123811 | 2019 | Nine novel HOGA1 gene mutations identified in primary hyperoxaluria type 3 and distinct clinical and biochemical characteristics in Chinese children. | 9 |
| 31401635 | 2019 | Mutation Hot Spot Region in the HOGA1 Gene Associated with Primary Hyperoxaluria Type 3 in the Chinese Population. | 3 |
| 31696211 | 2019 | Regulation of human 4-hydroxy-2-oxoglutarate aldolase by pyruvate and α-ketoglutarate: implications for primary hyperoxaluria type-3. | 7 |
| 31123811 | 2019 | Nine novel HOGA1 gene mutations identified in primary hyperoxaluria type 3 and distinct clinical and biochemical characteristics in Chinese children. | 9 |
| 31401635 | 2019 | Mutation Hot Spot Region in the HOGA1 Gene Associated with Primary Hyperoxaluria Type 3 in the Chinese Population. | 3 |
Citation
Dessen P
HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64378/hoga1-(4-hydroxy-2-oxoglutarate-aldolase-1)
