HOXB6 (homeobox B6)

2014-11-01 Affiliation

Identity

HGNC

HOXB6

LOCATION

17q21.32

LOCUSID

3216

ALIAS

HOX2,HOX2B,HU-2,Hox-2.2

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 3216
MIM: 142961
HGNC: 5117
Ensembl: ENSG00000108511

Variants:

dbSNP: 3216
ClinVar: 3216
TCGA: ENSG00000108511
COSMIC: HOXB6

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000108511	ENST00000225648	P17509
ENSG00000108511	ENST00000484302	P17509

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
22603795	2012	Evidence for a functional role of epigenetically regulated midcluster HOXB genes in the development of Barrett esophagus.	26
19477923	2009	Induction of HoxB transcription by retinoic acid requires actin polymerization.	23
17003840	2007	Mutation screening of BMP4, BMP7, HOXA4 and HOXB6 genes in Chinese patients with hypospadias.	13
15269212	2004	HOXB6 protein is bound to CREB-binding protein and represses globin expression in a DNA binding-dependent, PBX interaction-independent process.	11
29532406	2019	MicroRNA 196B Regulates HOXA5, HOXB6 and GLTP Expression Levels in Colorectal Cancer Cells.	3

Citation

Dessen P

HOXB6 (homeobox B6)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64392/hoxb6-(homeobox-b6)