HS3ST4 (heparan sulfate-glucosamine 3-sulfotransferase 4)

2014-11-01 Affiliation

Identity

HGNC

HS3ST4

LOCATION

16p12.1

LOCUSID

9951

ALIAS

3-OST-4,30ST4,3OST4,h3-OST-4

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 9951
MIM: 604059
HGNC: 5200
Ensembl: ENSG00000182601

Variants:

dbSNP: 9951
ClinVar: 9951
TCGA: ENSG00000182601
COSMIC: HS3ST4

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000182601	ENST00000331351	Q9Y661

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Metabolism	REACTOME	R-HSA-1430728
Metabolism of carbohydrates	REACTOME	R-HSA-71387
Glycosaminoglycan metabolism	REACTOME	R-HSA-1630316
Heparan sulfate/heparin (HS-GAG) metabolism	REACTOME	R-HSA-1638091
HS-GAG biosynthesis	REACTOME	R-HSA-2022928

References

Pubmed ID	Year	Title	Citations
34904858	2021	Heparan sulfate 3-O-sulfotransferase 4 is genetically associated with herpes zoster and enhances varicella-zoster virus-mediated fusogenic activity.	1
34904858	2021	Heparan sulfate 3-O-sulfotransferase 4 is genetically associated with herpes zoster and enhances varicella-zoster virus-mediated fusogenic activity.	1
25648963	2015	Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.	41
25648963	2015	Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.	41
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
18757372	2008	Tetrasulfated disaccharide unit in heparan sulfate: enzymatic formation and tissue distribution.	25
18757372	2008	Tetrasulfated disaccharide unit in heparan sulfate: enzymatic formation and tissue distribution.	25
17482450	2007	The principal neuronal gD-type 3-O-sulfotransferases and their products in central and peripheral nervous system tissues.	28
17482450	2007	The principal neuronal gD-type 3-O-sulfotransferases and their products in central and peripheral nervous system tissues.	28

Citation

Dessen P

HS3ST4 (heparan sulfate-glucosamine 3-sulfotransferase 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64429/hs3st4-(heparan-sulfate-glucosamine-3-sulfotransferase-4)