HTATSF1 (HIV-1 Tat specific factor 1)

2014-11-01 Affiliation

Identity

HGNC

HTATSF1

LOCATION

Xq26.3

LOCUSID

27336

ALIAS

TAT-SF1,TATSF1,dJ196E23.2

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 27336
MIM: 300346
HGNC: 5276
Ensembl: ENSG00000102241

Variants:

dbSNP: 27336
ClinVar: 27336
TCGA: ENSG00000102241
COSMIC: HTATSF1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000102241	ENST00000218364	O43719
ENSG00000102241	ENST00000425695	Q5H919
ENSG00000102241	ENST00000448450	Q5H918
ENSG00000102241	ENST00000535601	O43719

Expression (GTEx)

100

150

200

250

300

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
32016635	2020	Human Tat-specific factor 1 binds the HIV-1 genome and selectively transports HIV-1 RNAs.	3
32016635	2020	Human Tat-specific factor 1 binds the HIV-1 genome and selectively transports HIV-1 RNAs.	3
23153325	2012	Impact of sustained RNAi-mediated suppression of cellular cofactor Tat-SF1 on HIV-1 replication in CD4+ T cells.	4
23153325	2012	Impact of sustained RNAi-mediated suppression of cellular cofactor Tat-SF1 on HIV-1 replication in CD4+ T cells.	4
21282347	2011	Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing.	12
21282347	2011	Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing.	12
19479034	2009	Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs.	14
19479034	2009	Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs.	14
16512786	2006	Intracellular HIV-1 Tat protein represses constitutive LMP2 transcription increasing proteasome activity by interfering with the binding of IRF-1 to STAT1.	20
16512786	2006	Intracellular HIV-1 Tat protein represses constitutive LMP2 transcription increasing proteasome activity by interfering with the binding of IRF-1 to STAT1.	20
15050687	2004	Proliferation inhibition of astrocytes, neurons, and non-glial cells by intracellularly expressed human immunodeficiency virus type 1 (HIV-1) Tat protein.	19
15564463	2004	Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription.	43
15050687	2004	Proliferation inhibition of astrocytes, neurons, and non-glial cells by intracellularly expressed human immunodeficiency virus type 1 (HIV-1) Tat protein.	19
15564463	2004	Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription.	43

Citation

Dessen P

HTATSF1 (HIV-1 Tat specific factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64462/htatsf1-(hiv-1-tat-specific-factor-1)