Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 170572
MIM: 610121
HGNC: 24003
Ensembl: ENSG00000178084
Variants:
dbSNP: 170572
ClinVar: 170572
TCGA: ENSG00000178084
COSMIC: HTR3C
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000178084 | ENST00000318351 | Q8WXA8 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10352 | palonosetron | Chemical | VariantAnnotation | not associated | PD | 29177570 | |
| PA445048 | Nausea | Disease | VariantAnnotation | not associated | PD | 29177570 | |
| PA446051 | Vomiting | Disease | VariantAnnotation | not associated | PD | 29177570 | |
| PA449809 | granisetron | Chemical | VariantAnnotation | not associated | PD | 29177570 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 28813580 | 2017 | Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese. | 6 |
| 28813580 | 2017 | Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese. | 6 |
| 23928294 | 2014 | 5-HT3 receptor influences the washing phenotype and visual organization in obsessive-compulsive disorder supporting 5-HT3 receptor antagonists as novel treatment option. | 8 |
| 24477975 | 2014 | Association between variants of 5-hydroxytryptamine receptor 3C (HTR3C) and chemotherapy-induced symptoms in women receiving adjuvant treatment for breast cancer. | 6 |
| 23928294 | 2014 | 5-HT3 receptor influences the washing phenotype and visual organization in obsessive-compulsive disorder supporting 5-HT3 receptor antagonists as novel treatment option. | 8 |
| 24477975 | 2014 | Association between variants of 5-hydroxytryptamine receptor 3C (HTR3C) and chemotherapy-induced symptoms in women receiving adjuvant treatment for breast cancer. | 6 |
| 21192076 | 2011 | Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E. | 23 |
| 21192076 | 2011 | Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E. | 23 |
| 20021265 | 2010 | Two naturally occurring variants of the serotonin receptor gene HTR3C are associated with nausea in pregnancy. | 7 |
| 20021265 | 2010 | Two naturally occurring variants of the serotonin receptor gene HTR3C are associated with nausea in pregnancy. | 7 |
| 20356718 | 2010 | A coding variant of the novel serotonin receptor subunit 5-HT3E influences sustained attention in schizophrenia patients. | 8 |
| 20538960 | 2010 | A candidate gene study of obstructive sleep apnea in European Americans and African Americans. | 43 |
| 20021265 | 2010 | Two naturally occurring variants of the serotonin receptor gene HTR3C are associated with nausea in pregnancy. | 7 |
| 20021265 | 2010 | Two naturally occurring variants of the serotonin receptor gene HTR3C are associated with nausea in pregnancy. | 7 |
| 20356718 | 2010 | A coding variant of the novel serotonin receptor subunit 5-HT3E influences sustained attention in schizophrenia patients. | 8 |
Citation
Dessen P
HTR3C (5-hydroxytryptamine receptor 3C)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64469/htr3c-(5-hydroxytryptamine-receptor-3c)
