Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3363
MIM: 182137
HGNC: 5302
Ensembl: ENSG00000148680
Variants:
dbSNP: 3363
ClinVar: 3363
TCGA: ENSG00000148680
COSMIC: HTR7
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000148680 | ENST00000277874 | P34969 |
| ENSG00000148680 | ENST00000336152 | P34969 |
| ENSG00000148680 | ENST00000371719 | P34969 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA133950441 | hmg coa reductase inhibitors | Chemical | ClinicalAnnotation | associated | PD | 17600820 | |
| PA157379134 | Myalgia unspecified | Disease | ClinicalAnnotation | associated | PD | 17600820 | |
| PA164713257 | Selective serotonin reuptake inhibitors | Chemical | ClinicalAnnotation | associated | PD | 30874608 | |
| PA175 | GNAS | Gene | Pathway | associated | 19741567 | ||
| PA447278 | Depression | Disease | ClinicalAnnotation | associated | PD | 30874608 | |
| PA448500 | atorvastatin | Chemical | ClinicalAnnotation | associated | PD | 17600820 | |
| PA451089 | pravastatin | Chemical | ClinicalAnnotation | associated | PD | 17600820 | |
| PA451363 | simvastatin | Chemical | ClinicalAnnotation | associated | PD | 17600820 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36006564 | 2022 | Serotonin 5-HT7 receptor is a biomarker poor prognostic factor and induces proliferation of triple-negative breast cancer cells through FOXM1. | 4 |
| 36006564 | 2022 | Serotonin 5-HT7 receptor is a biomarker poor prognostic factor and induces proliferation of triple-negative breast cancer cells through FOXM1. | 4 |
| 33081564 | 2021 | Effects of 5-HT7 receptors on circadian rhythm of mice anesthetized with isoflurane. | 3 |
| 33528589 | 2021 | 5-HT7 receptors as a new target for prostate cancer physiopathology and treatment: an experimental study on PC-3 cells and FFPE tissues. | 5 |
| 34555475 | 2021 | 5-HT(7) receptors in Alzheimer's disease. | 4 |
| 33081564 | 2021 | Effects of 5-HT7 receptors on circadian rhythm of mice anesthetized with isoflurane. | 3 |
| 33528589 | 2021 | 5-HT7 receptors as a new target for prostate cancer physiopathology and treatment: an experimental study on PC-3 cells and FFPE tissues. | 5 |
| 34555475 | 2021 | 5-HT(7) receptors in Alzheimer's disease. | 4 |
| 31941109 | 2020 | Role of the Serotonin Receptor 7 in Brain Plasticity: From Development to Disease. | 26 |
| 31941109 | 2020 | Role of the Serotonin Receptor 7 in Brain Plasticity: From Development to Disease. | 26 |
| 30827505 | 2019 | MiRNA-29a modulates visceral hyperalgesia in irritable bowel syndrome by targeting HTR7. | 14 |
| 31172579 | 2019 | Stimulating DDX3 expression by serotonin 5-HT receptor 7 through phosphorylation of p53 via the AC-PKA-ERK signaling pathway. | 5 |
| 31892309 | 2019 | Role of 5-HT(7) receptors in the immune system in health and disease. | 26 |
| 30827505 | 2019 | MiRNA-29a modulates visceral hyperalgesia in irritable bowel syndrome by targeting HTR7. | 14 |
| 31172579 | 2019 | Stimulating DDX3 expression by serotonin 5-HT receptor 7 through phosphorylation of p53 via the AC-PKA-ERK signaling pathway. | 5 |
Citation
Dessen P
HTR7 (5-hydroxytryptamine receptor 7)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64475/htr7-(5-hydroxytryptamine-receptor-7)
