IBA57 (iron-sulfur cluster assembly factor IBA57)

2014-11-01  

Identity

HGNC
LOCATION
1q42.13
LOCUSID
ALIAS
C1orf69,MMDS3,SPG74
FUSION GENES

Other Information

Locus ID:

NCBI: 200205
MIM: 615316
HGNC: 27302
Ensembl: ENSG00000181873

Variants:

dbSNP: 200205
ClinVar: 200205
TCGA: ENSG00000181873
COSMIC: IBA57

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181873ENST00000366711Q5T440

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
318318562019Structural properties of [2Fe-2S] ISCA2-IBA57: a complex of the mitochondrial iron-sulfur cluster assembly machinery.14
318318562019Structural properties of [2Fe-2S] ISCA2-IBA57: a complex of the mitochondrial iron-sulfur cluster assembly machinery.14
286717262018Phenotypic spectrum of mutations in IBA57, a candidate gene for cavitating leukoencephalopathy.11
302582072018Expanding the phenotype of IBA57 mutations: related leukodystrophy can remain asymptomatic.9
286717262018Phenotypic spectrum of mutations in IBA57, a candidate gene for cavitating leukoencephalopathy.11
302582072018Expanding the phenotype of IBA57 mutations: related leukodystrophy can remain asymptomatic.9
277855682017Novel mutations in IBA57 are associated with leukodystrophy and variable clinical phenotypes.20
277855682017Novel mutations in IBA57 are associated with leukodystrophy and variable clinical phenotypes.20
256097682015Fe/S protein assembly gene IBA57 mutation causes hereditary spastic paraplegia.34
256097682015Fe/S protein assembly gene IBA57 mutation causes hereditary spastic paraplegia.34
234622912013Mutation of the iron-sulfur cluster assembly gene IBA57 causes severe myopathy and encephalopathy.52
234622912013Mutation of the iron-sulfur cluster assembly gene IBA57 causes severe myopathy and encephalopathy.52
223232892012The human mitochondrial ISCA1, ISCA2, and IBA57 proteins are required for [4Fe-4S] protein maturation.87
223232892012The human mitochondrial ISCA1, ISCA2, and IBA57 proteins are required for [4Fe-4S] protein maturation.87
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20

Citation

Dessen P

IBA57 (iron-sulfur cluster assembly factor IBA57)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64487/gene-explorer/meetings/