Identity
HGNC
LOCATION
6q23.3
LOCUSID
ALIAS
CRF2-10,CRF2-S1,CRF2X,IL-22BP,IL-22R-alpha-2,IL-22RA2,ZCYTOR16
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 116379
MIM: 606648
HGNC: 14901
Ensembl: ENSG00000164485
Variants:
dbSNP: 116379
ClinVar: 116379
TCGA: ENSG00000164485
COSMIC: IL22RA2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164485 | ENST00000296980 | Q969J5 |
| ENSG00000164485 | ENST00000339602 | Q969J5 |
| ENSG00000164485 | ENST00000349184 | Q969J5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37975916 | 2023 | Circulating apelin, IL22RA2 and VEGF in pre-capillary pulmonary hypertension. | 0 |
| 37975916 | 2023 | Circulating apelin, IL22RA2 and VEGF in pre-capillary pulmonary hypertension. | 0 |
| 34920229 | 2022 | Liver expression of IL-22, IL-22R1 and IL-22BP in patients with chronic hepatitis C with different fibrosis stages. | 1 |
| 36108991 | 2022 | Down-regulating Interleukin-22/Interleukin-22 binding protein axis promotes inflammation and aggravates diet-induced metabolic disorders. | 3 |
| 36311796 | 2022 | IL-22BP production is heterogeneously distributed in Crohn's disease. | 1 |
| 34920229 | 2022 | Liver expression of IL-22, IL-22R1 and IL-22BP in patients with chronic hepatitis C with different fibrosis stages. | 1 |
| 36108991 | 2022 | Down-regulating Interleukin-22/Interleukin-22 binding protein axis promotes inflammation and aggravates diet-induced metabolic disorders. | 3 |
| 36311796 | 2022 | IL-22BP production is heterogeneously distributed in Crohn's disease. | 1 |
| 33851257 | 2021 | The good and the bad about separation anxiety: roles of IL-22 and IL-22BP in liver pathologies. | 11 |
| 33851257 | 2021 | The good and the bad about separation anxiety: roles of IL-22 and IL-22BP in liver pathologies. | 11 |
| 31936765 | 2020 | The Rare IL22RA2 Signal Peptide Coding Variant rs28385692 Decreases Secretion of IL-22BP Isoform-1, -2 and -3 and Is Associated with Risk for Multiple Sclerosis. | 0 |
| 32632545 | 2020 | Elevated IL-22 in psoriasis plays an anti-apoptotic role in keratinocytes through mediating Bcl-xL/Bax. | 0 |
| 32955203 | 2020 | Low Interleukin-22 Binding Protein Is Associated With High Mortality in Alcoholic Hepatitis and Modulates Interleukin-22 Receptor Expression. | 5 |
| 31936765 | 2020 | The Rare IL22RA2 Signal Peptide Coding Variant rs28385692 Decreases Secretion of IL-22BP Isoform-1, -2 and -3 and Is Associated with Risk for Multiple Sclerosis. | 0 |
| 32632545 | 2020 | Elevated IL-22 in psoriasis plays an anti-apoptotic role in keratinocytes through mediating Bcl-xL/Bax. | 0 |
Citation
Dessen P
IL22RA2 (interleukin 22 receptor subunit alpha 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64597/il22ra2-(interleukin-22-receptor-subunit-alpha-2)
