Identity
HGNC
LOCATION
2q14.1
LOCUSID
ALIAS
FIL1,FIL1-(ETA),FIL1H,FILI-(ETA),IL-1F8,IL-1H2,IL1-ETA,IL1F8,IL1H2
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 27177
MIM: 605508
HGNC: 15564
Ensembl: ENSG00000136696
Variants:
dbSNP: 27177
ClinVar: 27177
TCGA: ENSG00000136696
COSMIC: IL36B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000136696 | ENST00000259213 | Q9NZH7 |
| ENSG00000136696 | ENST00000327407 | Q9NZH7 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Cytokine Signaling in Immune system | REACTOME | R-HSA-1280215 |
| Signaling by Interleukins | REACTOME | R-HSA-449147 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38189700 | 2024 | Emerging Role of the IL-36/IL-36R Axis in Multiple Inflammatory Skin Diseases. | 2 |
| 38189700 | 2024 | Emerging Role of the IL-36/IL-36R Axis in Multiple Inflammatory Skin Diseases. | 2 |
| 37446281 | 2023 | Increased Interleukin-36β Expression Promotes Angiogenesis in Japanese Atopic Dermatitis. | 2 |
| 37446281 | 2023 | Increased Interleukin-36β Expression Promotes Angiogenesis in Japanese Atopic Dermatitis. | 2 |
| 35698471 | 2022 | IL-36 is Closely Related to Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease. | 0 |
| 35903102 | 2022 | IL-36 Cytokines: Their Roles in Asthma and Potential as a Therapeutic. | 5 |
| 35698471 | 2022 | IL-36 is Closely Related to Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease. | 0 |
| 35903102 | 2022 | IL-36 Cytokines: Their Roles in Asthma and Potential as a Therapeutic. | 5 |
| 32013927 | 2020 | IL-36 s in the colorectal cancer: is interleukin 36 good or bad for the development of colorectal cancer? | 18 |
| 32013927 | 2020 | IL-36 s in the colorectal cancer: is interleukin 36 good or bad for the development of colorectal cancer? | 18 |
| 31601303 | 2019 | IL-36β Promotes Inflammatory Activity and Inhibits Differentiation of Keratinocytes In Vitro. | 1 |
| 31736959 | 2019 | Biology of IL-36 Signaling and Its Role in Systemic Inflammatory Diseases. | 46 |
| 31601303 | 2019 | IL-36β Promotes Inflammatory Activity and Inhibits Differentiation of Keratinocytes In Vitro. | 1 |
| 31736959 | 2019 | Biology of IL-36 Signaling and Its Role in Systemic Inflammatory Diseases. | 46 |
| 28811383 | 2017 | Interleukin-36 cytokines may overcome microbial immune evasion strategies that inhibit interleukin-1 family signaling. | 20 |
Citation
Dessen P
IL36B (interleukin 36 beta)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64601/il36b-(interleukin-36-beta)
