Identity
HGNC
LOCATION
9q22.31
LOCUSID
ALIAS
C9orf12,INSP5K2,IP5K,IPK1,bA476B13.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64768
HGNC: 14645
Ensembl: ENSG00000127080
Variants:
dbSNP: 64768
ClinVar: 64768
TCGA: ENSG00000127080
COSMIC: IPPK
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000127080 | ENST00000287996 | Q9H8X2 |
| ENSG00000127080 | ENST00000375522 | X6R9A6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29746542 | 2018 | Depletion of mRNA export regulator DBP5/DDX19, GLE1 or IPPK that is a key enzyme for the production of IP6, resulting in differentially altered cytoplasmic mRNA expression and specific cell defect. | 13 |
| 30132343 | 2018 | Urine inositol pentakisphosphate 2-kinase and changes in kidney structure in early diabetic kidney disease in type 1 diabetes. | 1 |
| 29746542 | 2018 | Depletion of mRNA export regulator DBP5/DDX19, GLE1 or IPPK that is a key enzyme for the production of IP6, resulting in differentially altered cytoplasmic mRNA expression and specific cell defect. | 13 |
| 30132343 | 2018 | Urine inositol pentakisphosphate 2-kinase and changes in kidney structure in early diabetic kidney disease in type 1 diabetes. | 1 |
| 26976604 | 2016 | Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function. | 20 |
| 26976604 | 2016 | Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function. | 20 |
| 24165122 | 2013 | Conformational stability of inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IPK1) dictates its substrate selectivity. | 2 |
| 24165122 | 2013 | Conformational stability of inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IPK1) dictates its substrate selectivity. | 2 |
| 12084730 | 2002 | The synthesis of inositol hexakisphosphate. Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase. | 37 |
| 12084730 | 2002 | The synthesis of inositol hexakisphosphate. Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase. | 37 |
Citation
Dessen P
IPPK (inositol-pentakisphosphate 2-kinase)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64642/ippk-(inositol-pentakisphosphate-2-kinase)
