IRX6 (iroquois homeobox 6)

2014-11-01 Affiliation

Identity

HGNC

IRX6

LOCATION

16q12.2

LOCUSID

79190

ALIAS

IRX-3,IRX7,IRXB3

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 79190
MIM: 606196
HGNC: 14675
Ensembl: ENSG00000159387

Variants:

dbSNP: 79190
ClinVar: 79190
TCGA: ENSG00000159387
COSMIC: IRX6

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000159387	ENST00000290552	P78412

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
33891002	2021	A duplication on chromosome 16q12 affecting the IRXB gene cluster is associated with autosomal dominant cone dystrophy with early tritanopic color vision defect.	2
33891002	2021	A duplication on chromosome 16q12 affecting the IRXB gene cluster is associated with autosomal dominant cone dystrophy with early tritanopic color vision defect.	2
30063927	2019	Single Nucleotide Polymorphisms of HAAO and IRX6 Genes as Risk Factors for Hypospadias.	4
30063927	2019	Single Nucleotide Polymorphisms of HAAO and IRX6 Genes as Risk Factors for Hypospadias.	4

Citation

Dessen P

IRX6 (iroquois homeobox 6)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64666/irx6-(iroquois-homeobox-6)