ISOC1 (isochorismatase domain containing 1)

2014-11-01  

Identity

HGNC
ISOC1
LOCATION
5q23.3
LOCUSID
51015
ALIAS
CGI-111

Other Information

Locus ID:

NCBI: 51015
HGNC: 24254
Ensembl: ENSG00000066583

Variants:

dbSNP: 51015
ClinVar: 51015
TCGA: ENSG00000066583
COSMIC: ISOC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000066583ENST00000173527Q96CN7
ENSG00000066583ENST00000514194D6RGE2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
335471712021Functional Analysis of Immune Signature Genes in Th1* Memory Cells Links ISOC1 and Pyrimidine Metabolism to IFN-γ and IL-17 Production.7
335471712021Functional Analysis of Immune Signature Genes in Th1* Memory Cells Links ISOC1 and Pyrimidine Metabolism to IFN-γ and IL-17 Production.7
317409422020Knockdown of ISOC1 inhibits the proliferation and migration and induces the apoptosis of colon cancer cells through the AKT/GSK-3β pathway.7
332752272020ISOC1 promotes the proliferation of gastric cancer cells by positively regulating CDK19.5
317409422020Knockdown of ISOC1 inhibits the proliferation and migration and induces the apoptosis of colon cancer cells through the AKT/GSK-3β pathway.7
332752272020ISOC1 promotes the proliferation of gastric cancer cells by positively regulating CDK19.5

Citation

Dessen P

ISOC1 (isochorismatase domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64676/isoc1-(isochorismatase-domain-containing-1)