JMJD7-PLA2G4B (JMJD7-PLA2G4B readthrough)

2014-11-01  

Identity

HGNC
JMJD7-PLA2G4B
LOCATION
15q15.1
LOCUSID
8681
ALIAS
HsT16992,cPLA2-beta
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8681
HGNC: 34449
Ensembl: ENSG00000168970

Variants:

dbSNP: 8681
ClinVar: 8681
TCGA: ENSG00000168970
COSMIC: JMJD7-PLA2G4B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168970ENST00000487292H0Y9G9

Pathways

PathwaySourceExternal ID
Glycerophospholipid metabolismKEGGko00564
Ether lipid metabolismKEGGko00565
Arachidonic acid metabolismKEGGko00590
Linoleic acid metabolismKEGGko00591
alpha-Linolenic acid metabolismKEGGko00592
MAPK signaling pathwayKEGGko04010
VEGF signaling pathwayKEGGko04370
Fc epsilon RI signaling pathwayKEGGko04664
Long-term depressionKEGGko04730
GnRH signaling pathwayKEGGko04912
Glycerophospholipid metabolismKEGGhsa00564
Ether lipid metabolismKEGGhsa00565
Arachidonic acid metabolismKEGGhsa00590
Linoleic acid metabolismKEGGhsa00591
alpha-Linolenic acid metabolismKEGGhsa00592
MAPK signaling pathwayKEGGhsa04010
VEGF signaling pathwayKEGGhsa04370
Fc epsilon RI signaling pathwayKEGGhsa04664
Long-term depressionKEGGhsa04730
GnRH signaling pathwayKEGGhsa04912
Vascular smooth muscle contractionKEGGhsa04270
Vascular smooth muscle contractionKEGGko04270
Metabolic pathwaysKEGGhsa01100
Glutamatergic synapseKEGGko04724
Glutamatergic synapseKEGGhsa04724
Serotonergic synapseKEGGhsa04726
Ovarian steroidogenesisKEGGhsa04913
Ovarian steroidogenesisKEGGko04913
Ras signaling pathwayKEGGhsa04014
Inflammatory mediator regulation of TRP channelsKEGGhsa04750
Inflammatory mediator regulation of TRP channelsKEGGko04750
Platelet activationKEGGhsa04611
Oxytocin signaling pathwayKEGGhsa04921
Oxytocin signaling pathwayKEGGko04921
Choline metabolism in cancerKEGGhsa05231
Choline metabolism in cancerKEGGko05231
Phospholipase D signaling pathwayKEGGko04072
Phospholipase D signaling pathwayKEGGhsa04072

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
adipose tissue
skin 1
appendix
spleen
lymph node
tonsil

References

Pubmed IDYearTitleCitations
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105
159993432005Cytosolic PLA2 genes possibly contribute to the etiology of schizophrenia.4
159993432005Cytosolic PLA2 genes possibly contribute to the etiology of schizophrenia.4
152740492004Association analysis of two candidate phospholipase genes that map to the chromosome 15q15.1-15.3 region associated with reading disability.2
152740492004Association analysis of two candidate phospholipase genes that map to the chromosome 15q15.1-15.3 region associated with reading disability.2
117418842002Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis.63
117418842002Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis.63

Citation

Dessen P

JMJD7-PLA2G4B (JMJD7-PLA2G4B readthrough)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64721/jmjd7-pla2g4b-(jmjd7-pla2g4b-readthrough)