KANK4 (KN motif and ankyrin repeat domains 4)

2014-11-01  

Identity

HGNC
LOCATION
1p31.3
LOCUSID
ALIAS
ANKRD38,dJ1078M7.1
FUSION GENES

Other Information

Locus ID:

NCBI: 163782
MIM: 614612
HGNC: 27263
Ensembl: ENSG00000132854

Variants:

dbSNP: 163782
ClinVar: 163782
TCGA: ENSG00000132854
COSMIC: KANK4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132854ENST00000317477B1ALP5
ENSG00000132854ENST00000354381Q5T7N3
ENSG00000132854ENST00000371150B1ALP6
ENSG00000132854ENST00000371153Q5T7N3

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382116482024DHCR7 promotes lymph node metastasis in cervical cancer through cholesterol reprogramming-mediated activation of the KANK4/PI3K/AKT axis and VEGF-C secretion.0
386222562024Exclusive expression of KANK4 promotes myofibroblast mobility in keloid tissues.0
382116482024DHCR7 promotes lymph node metastasis in cervical cancer through cholesterol reprogramming-mediated activation of the KANK4/PI3K/AKT axis and VEGF-C secretion.0
386222562024Exclusive expression of KANK4 promotes myofibroblast mobility in keloid tissues.0
299131992019Genome-wide profiling of adult human papillary and reticular fibroblasts identifies ACAN, Col XI α1, and PSG1 as general biomarkers of dermis ageing, and KANK4 as an exemplary effector of papillary fibroblast ageing, related to contractility.14
299131992019Genome-wide profiling of adult human papillary and reticular fibroblasts identifies ACAN, Col XI α1, and PSG1 as general biomarkers of dermis ageing, and KANK4 as an exemplary effector of papillary fibroblast ageing, related to contractility.14
259614572015KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.103
259614572015KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.103

Citation

Dessen P

KANK4 (KN motif and ankyrin repeat domains 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64736/kank4-(kn-motif-and-ankyrin-repeat-domains-4)