KCNE4 (potassium voltage-gated channel subfamily E regulatory subunit 4)

2014-11-01  

Identity

HGNC
LOCATION
2q36.1
LOCUSID
ALIAS
MIRP3

Other Information

Locus ID:

NCBI: 23704
MIM: 607775
HGNC: 6244
Ensembl: ENSG00000152049

Variants:

dbSNP: 23704
ClinVar: 23704
TCGA: ENSG00000152049
COSMIC: KCNE4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000152049ENST00000281830Q8WWG9

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Muscle contractionREACTOMER-HSA-397014
Cardiac conductionREACTOMER-HSA-5576891
Phase 2 - plateau phaseREACTOMER-HSA-5576893
Phase 3 - rapid repolarisationREACTOMER-HSA-5576890

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
364598332023KCNE4 expression is correlated with the pathological characteristics of colorectal cancer patients and associated with the radioresistance of cancer cells.3
375697252023Vitamin D Receptor Deficiency Upregulates Pulmonary Artery Kv7 Channel Activity.1
364598332023KCNE4 expression is correlated with the pathological characteristics of colorectal cancer patients and associated with the radioresistance of cancer cells.3
375697252023Vitamin D Receptor Deficiency Upregulates Pulmonary Artery Kv7 Channel Activity.1
359150772022Induction of potassium channel regulator KCNE4 in a submandibular lymph node metastasis model.0
359150772022Induction of potassium channel regulator KCNE4 in a submandibular lymph node metastasis model.0
342342412021Calmodulin-dependent KCNE4 dimerization controls membrane targeting.4
342724512021KCNE4-dependent functional consequences of Kv1.3-related leukocyte physiology.2
342342412021Calmodulin-dependent KCNE4 dimerization controls membrane targeting.4
342724512021KCNE4-dependent functional consequences of Kv1.3-related leukocyte physiology.2
309697952019The calmodulin-binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3.7
309697952019The calmodulin-binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3.7
289819462017[Association of KCNE1 and KCNE4 gene polymorphisms with atrial fibrillation among Uygur and Han Chinese populations in Xinjiang].2
289819462017[Association of KCNE1 and KCNE4 gene polymorphisms with atrial fibrillation among Uygur and Han Chinese populations in Xinjiang].2
271620252016Novel exon 1 protein-coding regions N-terminally extend human KCNE3 and KCNE4.8

Citation

Dessen P

KCNE4 (potassium voltage-gated channel subfamily E regulatory subunit 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64775/kcne4-(potassium-voltage-gated-channel-subfamily-e-regulatory-subunit-4)