KCNG4 (potassium voltage-gated channel modifier subfamily G member 4)

2014-11-01  

Identity

HGNC
LOCATION
16q24.1
LOCUSID
ALIAS
KV6.3,KV6.4

Other Information

Locus ID:

NCBI: 93107
MIM: 607603
HGNC: 19697
Ensembl: ENSG00000168418

Variants:

dbSNP: 93107
ClinVar: 93107
TCGA: ENSG00000168418
COSMIC: KCNG4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168418ENST00000308251Q8TDN1
ENSG00000168418ENST00000308251Q547S7
ENSG00000168418ENST00000568181Q8TDN1

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Potassium ChannelsREACTOMER-HSA-1296071
Voltage gated Potassium channelsREACTOMER-HSA-1296072

References

Pubmed IDYearTitleCitations
326979882020Human Labor Pain Is Influenced by the Voltage-Gated Potassium Channel K(V)6.4 Subunit.13
326979882020Human Labor Pain Is Influenced by the Voltage-Gated Potassium Channel K(V)6.4 Subunit.13
262427572015Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels.14
265054742015Modulation of Closed-State Inactivation in Kv2.1/Kv6.4 Heterotetramers as Mechanism for 4-AP Induced Potentiation.10
262427572015Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels.14
265054742015Modulation of Closed-State Inactivation in Kv2.1/Kv6.4 Heterotetramers as Mechanism for 4-AP Induced Potentiation.10
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
190741352009Mutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4.13
190741352009Mutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4.13
160963422005Domain analysis of Kv6.3, an electrically silent channel.14
160963422005Domain analysis of Kv6.3, an electrically silent channel.14
120607452002Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.58
120607452002Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.58

Citation

Dessen P

KCNG4 (potassium voltage-gated channel modifier subfamily G member 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64779/kcng4-(potassium-voltage-gated-channel-modifier-subfamily-g-member-4)