ANP32B (acidic nuclear phosphoprotein 32 family member B)

2003-11-01  

Identity

HGNC
LOCATION
9q22.33
LOCUSID
ALIAS
APRIL,PHAPI2,SSP29
FUSION GENES

Other Information

Locus ID:

NCBI: 10541
HGNC: 16677
Ensembl: ENSG00000136938

Variants:

dbSNP: 10541
ClinVar: 10541
TCGA: ENSG00000136938
COSMIC: ANP32B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136938ENST00000339399Q92688

Expression (GTEx)

0
100
200
300
400
500
600

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
125222432003Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway.89
200158642010Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells.22
309960882019Fundamental Contribution and Host Range Determination of ANP32A and ANP32B in Influenza A Virus Polymerase Activity.14
180398462008Promoter region-specific histone incorporation by the novel histone chaperone ANP32B and DNA-binding factor KLF5.13
205380072010Solution structure of histone chaperone ANP32B: interaction with core histones H3-H4 through its acidic concave domain.13
191305532009Phosphorylation of the HuR ligand APRIL by casein kinase 2 regulates CD83 expression.12
248239482014ANP32B is a nuclear target of henipavirus M proteins.12
311599252019Species specific differences in use of ANP32 proteins by influenza A virus.11
227053002012Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) contributes to retinoic acid-induced differentiation of leukemic cells.7
254837092015Caspase-3-resistant uncleavable form of acidic leucine-rich nuclear phosphoprotein 32B potentiates leukemic cell apoptosis.3

Citation

Dessen P

ANP32B (acidic nuclear phosphoprotein 32 family member B)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/648/anp32b-(acidic-nuclear-phosphoprotein-32-family-member-b)