Identity
HGNC
LOCATION
5q22.3
LOCUSID
ALIAS
KCa2.2,SK2,SKCA2,SKCa 2,hSK2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3781
MIM: 605879
HGNC: 6291
Ensembl: ENSG00000080709
Variants:
dbSNP: 3781
ClinVar: 3781
TCGA: ENSG00000080709
COSMIC: KCNN2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36502918 | 2023 | Preferential formation of human heteromeric SK2:SK3 channels limits homomeric SK channel assembly and function. | 2 |
| 36717104 | 2023 | Loss-of-function K(Ca)2.2 mutations abolish channel activity. | 2 |
| 37510285 | 2023 | A Novel KCNN2 Variant in a Family with Essential Tremor Plus: Clinical Characteristics and In Silico Analysis. | 2 |
| 36502918 | 2023 | Preferential formation of human heteromeric SK2:SK3 channels limits homomeric SK channel assembly and function. | 2 |
| 36717104 | 2023 | Loss-of-function K(Ca)2.2 mutations abolish channel activity. | 2 |
| 37510285 | 2023 | A Novel KCNN2 Variant in a Family with Essential Tremor Plus: Clinical Characteristics and In Silico Analysis. | 2 |
| 33310041 | 2021 | HDAC2-dependent remodeling of K(Ca)2.2 (KCNN2) and K(Ca)2.3 (KCNN3) K(+) channels in atrial fibrillation with concomitant heart failure. | 7 |
| 33310041 | 2021 | HDAC2-dependent remodeling of K(Ca)2.2 (KCNN2) and K(Ca)2.3 (KCNN3) K(+) channels in atrial fibrillation with concomitant heart failure. | 7 |
| 32212350 | 2020 | KCNN2 mutation in autosomal-dominant tremulous myoclonus-dystonia. | 12 |
| 32860835 | 2020 | SK2 channel regulation of neuronal excitability, synaptic transmission, and brain rhythmic activity in health and diseases. | 15 |
| 33242881 | 2020 | Variants in the SK2 channel gene (KCNN2) lead to dominant neurodevelopmental movement disorders. | 20 |
| 32212350 | 2020 | KCNN2 mutation in autosomal-dominant tremulous myoclonus-dystonia. | 12 |
| 32860835 | 2020 | SK2 channel regulation of neuronal excitability, synaptic transmission, and brain rhythmic activity in health and diseases. | 15 |
| 33242881 | 2020 | Variants in the SK2 channel gene (KCNN2) lead to dominant neurodevelopmental movement disorders. | 20 |
| 30922569 | 2019 | Role of SK channel activation in determining the action potential configuration in freshly isolated human atrial myocytes from the SKArF study. | 6 |
Citation
Dessen P
KCNN2 (potassium calcium-activated channel subfamily N member 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64804/
