KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1)

2014-11-01  

Identity

HGNC
LOCATION
19q13.33
LOCUSID
ALIAS
ERD2,ERD2.1,HDEL,PM23
FUSION GENES

Other Information

Locus ID:

NCBI: 10945
MIM: 131235
HGNC: 6304
Ensembl: ENSG00000105438

Variants:

dbSNP: 10945
ClinVar: 10945
TCGA: ENSG00000105438
COSMIC: KDELR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105438ENST00000330720P24390
ENSG00000105438ENST00000597017P24390
ENSG00000105438ENST00000600980M0R1Y2

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Pathways

PathwaySourceExternal ID
Vibrio cholerae infectionKEGGko05110
Vibrio cholerae infectionKEGGhsa05110
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
COPI-mediated anterograde transportREACTOMER-HSA-6807878
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-dependent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811434

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
325620232021KDEL receptor is a cell surface receptor that cycles between the plasma membrane and the Golgi via clathrin-mediated transport carriers.15
325620232021KDEL receptor is a cell surface receptor that cycles between the plasma membrane and the Golgi via clathrin-mediated transport carriers.15
326451012020Cell-type-specific differences in KDEL receptor clustering in mammalian cells.6
326451012020Cell-type-specific differences in KDEL receptor clustering in mammalian cells.6
307607042019KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover.24
309586602019KDEL Receptor 1 Contributes to Cell Surface Association of Protein Disulfide Isomerases.12
313378612019Transcriptomics of a KDELR1 knockout cell line reveals modulated cell adhesion properties.6
307607042019KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover.24
309586602019KDEL Receptor 1 Contributes to Cell Surface Association of Protein Disulfide Isomerases.12
313378612019Transcriptomics of a KDELR1 knockout cell line reveals modulated cell adhesion properties.6
268613842016A KDEL Retrieval System for ER-Golgi Transport of Japanese Encephalitis Viral Particles.9
268613842016A KDEL Retrieval System for ER-Golgi Transport of Japanese Encephalitis Viral Particles.9
256828662015A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation.21
260648972015Prohibitin: A Novel Molecular Player in KDEL Receptor Signalling.8
256828662015A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation.21

Citation

Dessen P

KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64833/kdelr1-(kdel-endoplasmic-reticulum-protein-retention-receptor-1)