Identity
HGNC
LOCATION
14q13.2
LOCUSID
ALIAS
KIAA0391,MRPP3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9692
MIM: 609947
HGNC: 19958
Ensembl: ENSG00000258790
Variants:
dbSNP: 9692
ClinVar: 9692
TCGA: ENSG00000258790
COSMIC: PRORP
RNA/Proteins
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443450 | Asthma | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | 25963335 | |
| PA451955 | zileuton | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | 25963335 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38262497 | 2024 | Comprehensive functional interrogation of susceptibility loci in GWASs identified KIAA0391 as a novel oncogenic driver via regulating pyroptosis in NSCLC. | 0 |
| 38262497 | 2024 | Comprehensive functional interrogation of susceptibility loci in GWASs identified KIAA0391 as a novel oncogenic driver via regulating pyroptosis in NSCLC. | 0 |
| 37558808 | 2023 | Novel homozygous variants in PRORP expand the genotypic spectrum of combined oxidative phosphorylation deficiency 54. | 2 |
| 37558808 | 2023 | Novel homozygous variants in PRORP expand the genotypic spectrum of combined oxidative phosphorylation deficiency 54. | 2 |
| 34489609 | 2021 | Structural basis of RNA processing by human mitochondrial RNase P. | 32 |
| 34715011 | 2021 | Bi-allelic variants in the mitochondrial RNase P subunit PRORP cause mitochondrial tRNA processing defects and pleiotropic multisystem presentations. | 23 |
| 34489609 | 2021 | Structural basis of RNA processing by human mitochondrial RNase P. | 32 |
| 34715011 | 2021 | Bi-allelic variants in the mitochondrial RNase P subunit PRORP cause mitochondrial tRNA processing defects and pleiotropic multisystem presentations. | 23 |
| 29880640 | 2018 | Structural insight into the human mitochondrial tRNA purine N1-methyltransferase and ribonuclease P complexes. | 18 |
| 29880640 | 2018 | Structural insight into the human mitochondrial tRNA purine N1-methyltransferase and ribonuclease P complexes. | 18 |
| 25953853 | 2015 | Structure of the nuclease subunit of human mitochondrial RNase P. | 29 |
| 25953853 | 2015 | Structure of the nuclease subunit of human mitochondrial RNase P. | 29 |
| 24763589 | 2014 | High-resolution genomic analysis of human mitochondrial RNA sequence variation. | 53 |
| 24763589 | 2014 | High-resolution genomic analysis of human mitochondrial RNA sequence variation. | 53 |
| 23755257 | 2013 | The amyloid-β-SDR5C1(ABAD) interaction does not mediate a specific inhibition of mitochondrial RNase P. | 4 |
Citation
Dessen P
PRORP (protein only RNase P catalytic subunit)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64855/prorp-(protein-only-rnase-p-catalytic-subunit)
