Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57576
MIM: 605037
HGNC: 19167
Ensembl: ENSG00000117245
Variants:
dbSNP: 57576
ClinVar: 57576
TCGA: ENSG00000117245
COSMIC: KIF17
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000117245 | ENST00000247986 | Q9P2E2 |
| ENSG00000117245 | ENST00000375044 | A0A0A0MRS8 |
| ENSG00000117245 | ENST00000400463 | Q9P2E2 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Organelle biogenesis and maintenance | REACTOME | R-HSA-1852241 |
| Cilium Assembly | REACTOME | R-HSA-5617833 |
| Intraflagellar transport | REACTOME | R-HSA-5620924 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33922911 | 2021 | Biallelic Variants in KIF17 Associated with Microphthalmia and Coloboma Spectrum. | 2 |
| 33922911 | 2021 | Biallelic Variants in KIF17 Associated with Microphthalmia and Coloboma Spectrum. | 2 |
| 28077622 | 2017 | Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal. | 32 |
| 28761002 | 2017 | Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load. | 28 |
| 28077622 | 2017 | Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal. | 32 |
| 28761002 | 2017 | Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load. | 28 |
| 26759174 | 2016 | KIF17 regulates RhoA-dependent actin remodeling at epithelial cell-cell adhesions. | 8 |
| 26823018 | 2016 | Septin 9 interacts with kinesin KIF17 and interferes with the mechanism of NMDA receptor cargo binding and transport. | 24 |
| 26759174 | 2016 | KIF17 regulates RhoA-dependent actin remodeling at epithelial cell-cell adhesions. | 8 |
| 26823018 | 2016 | Septin 9 interacts with kinesin KIF17 and interferes with the mechanism of NMDA receptor cargo binding and transport. | 24 |
| 26421900 | 2015 | A decrease in protein level and a missense polymorphism of KIF17 are associated with schizophrenia. | 1 |
| 26421900 | 2015 | A decrease in protein level and a missense polymorphism of KIF17 are associated with schizophrenia. | 1 |
| 24072717 | 2013 | Direct regulation of microtubule dynamics by KIF17 motor and tail domains. | 13 |
| 24072717 | 2013 | Direct regulation of microtubule dynamics by KIF17 motor and tail domains. | 13 |
| 20378615 | 2010 | Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent. | 61 |
Citation
Dessen P
KIF17 (kinesin family member 17)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64914/deep-insight-explorer/meetings/
