KIF21B (kinesin family member 21B)

2014-11-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 23046
MIM: 608322
HGNC: 29442
Ensembl: ENSG00000116852

Variants:

dbSNP: 23046
ClinVar: 23046
TCGA: ENSG00000116852
COSMIC: KIF21B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116852ENST00000332129O75037
ENSG00000116852ENST00000360529O75037
ENSG00000116852ENST00000422435O75037
ENSG00000116852ENST00000461742O75037

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Factors involved in megakaryocyte development and platelet productionREACTOMER-HSA-983231
KinesinsREACTOMER-HSA-983189
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-dependent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811434

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
353414462022Targeting kinesin family member 21B by miR-132-3p represses cell proliferation, migration and invasion in gastric cancer.3
353414462022Targeting kinesin family member 21B by miR-132-3p represses cell proliferation, migration and invasion in gastric cancer.3
324151092020Mutations in the KIF21B kinesin gene cause neurodevelopmental disorders through imbalanced canonical motor activity.18
333467302020Kinesin-4 KIF21B limits microtubule growth to allow rapid centrosome polarization in T cells.18
324151092020Mutations in the KIF21B kinesin gene cause neurodevelopmental disorders through imbalanced canonical motor activity.18
333467302020Kinesin-4 KIF21B limits microtubule growth to allow rapid centrosome polarization in T cells.18
282909842017Kinesin-4 KIF21B is a potent microtubule pausing factor.33
282909842017Kinesin-4 KIF21B is a potent microtubule pausing factor.33
251496462015Association of KIF21B genetic polymorphisms with ankylosing spondylitis in a Chinese Han population of Shandong Province.7
251496462015Association of KIF21B genetic polymorphisms with ankylosing spondylitis in a Chinese Han population of Shandong Province.7
240653532013Association of common variants in KIF21B and ankylosing spondylitis in a Chinese Han population: a replication study.4
240653532013Association of common variants in KIF21B and ankylosing spondylitis in a Chinese Han population: a replication study.4
200075042010Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci.53
205874132010Replication of KIF21B as a susceptibility locus for multiple sclerosis.17
205874132010Replication of KIF21B as a susceptibility locus for multiple sclerosis.17

Citation

Dessen P

KIF21B (kinesin family member 21B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64920/kif21b-(kinesin-family-member-21b)