Identity
HGNC
LOCATION
15q26.1
LOCUSID
ALIAS
ACLS,AGBK,HLS2,JBTS12,UNQ340
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 374654
MIM: 611254
HGNC: 30497
Ensembl: ENSG00000166813
Variants:
dbSNP: 374654
ClinVar: 374654
TCGA: ENSG00000166813
COSMIC: KIF7
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166813 | ENST00000394412 | Q2M1P5 |
| ENSG00000166813 | ENST00000445906 | F8WD21 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33382518 | 2021 | Mutations in KIF7 implicated in idiopathic scoliosis in humans and axial curvatures in zebrafish. | 16 |
| 34114033 | 2021 | Sequences in the stalk domain regulate auto-inhibition and ciliary tip localization of the immotile kinesin-4 KIF7. | 5 |
| 33382518 | 2021 | Mutations in KIF7 implicated in idiopathic scoliosis in humans and axial curvatures in zebrafish. | 16 |
| 34114033 | 2021 | Sequences in the stalk domain regulate auto-inhibition and ciliary tip localization of the immotile kinesin-4 KIF7. | 5 |
| 32164589 | 2020 | Co-occurrence of mutations in KIF7 and KIAA0556 in Joubert syndrome with ocular coloboma, pituitary malformation and growth hormone deficiency: a case report and literature review. | 8 |
| 32738303 | 2020 | Identification of novel candidate genes in heterotaxy syndrome patients with congenital heart diseases by whole exome sequencing. | 15 |
| 32945133 | 2020 | Human papillomavirus 16 (HPV 16) E6 but not E7 inhibits the antitumor activity of LKB1 in lung cancer cells by downregulating the expression of KIF7. | 5 |
| 32164589 | 2020 | Co-occurrence of mutations in KIF7 and KIAA0556 in Joubert syndrome with ocular coloboma, pituitary malformation and growth hormone deficiency: a case report and literature review. | 8 |
| 32738303 | 2020 | Identification of novel candidate genes in heterotaxy syndrome patients with congenital heart diseases by whole exome sequencing. | 15 |
| 32945133 | 2020 | Human papillomavirus 16 (HPV 16) E6 but not E7 inhibits the antitumor activity of LKB1 in lung cancer cells by downregulating the expression of KIF7. | 5 |
| 31658044 | 2019 | Low expression of KIF7 indicates poor prognosis in epithelial ovarian cancer. | 7 |
| 31658044 | 2019 | Low expression of KIF7 indicates poor prognosis in epithelial ovarian cancer. | 7 |
| 25714560 | 2015 | A novel KIF7 mutation in two affected siblings with acrocallosal syndrome. | 4 |
| 26174511 | 2015 | Novel KIF7 missense substitutions in two patients presenting with multiple malformations and features of acrocallosal syndrome. | 10 |
| 25714560 | 2015 | A novel KIF7 mutation in two affected siblings with acrocallosal syndrome. | 4 |
Citation
Dessen P
KIF7 (kinesin family member 7)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64929/kif7-(kinesin-family-member-7)
