Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 59349
MIM: 614522
HGNC: 19360
Ensembl: ENSG00000117153
Variants:
dbSNP: 59349
ClinVar: 59349
TCGA: ENSG00000117153
COSMIC: KLHL12
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000117153 | ENST00000367258 | J3QSX3 |
| ENSG00000117153 | ENST00000367259 | Q9H7R2 |
| ENSG00000117153 | ENST00000367261 | Q53G59 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32433973 | 2020 | Ubiquitylation of the ER-Shaping Protein Lunapark via the CRL3(KLHL12) Ubiquitin Ligase Complex. | 8 |
| 32574548 | 2020 | Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12. | 6 |
| 32433973 | 2020 | Ubiquitylation of the ER-Shaping Protein Lunapark via the CRL3(KLHL12) Ubiquitin Ligase Complex. | 8 |
| 32574548 | 2020 | Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12. | 6 |
| 27899653 | 2017 | Control of the negative IRES trans-acting factor KHSRP by ubiquitination. | 14 |
| 27899653 | 2017 | Control of the negative IRES trans-acting factor KHSRP by ubiquitination. | 14 |
| 27155323 | 2016 | Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins. | 3 |
| 27155323 | 2016 | Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins. | 3 |
| 26717573 | 2015 | KLHL12 Promotes Non-Lysine Ubiquitination of the Dopamine Receptors D4.2 and D4.4, but Not of the ADHD-Associated D4.7 Variant. | 6 |
| 26717573 | 2015 | KLHL12 Promotes Non-Lysine Ubiquitination of the Dopamine Receptors D4.2 and D4.4, but Not of the ADHD-Associated D4.7 Variant. | 6 |
| 19536175 | 2009 | Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. | 32 |
| 19536175 | 2009 | Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. | 32 |
| 18303015 | 2008 | BTB Protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase. | 40 |
| 18303015 | 2008 | BTB Protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase. | 40 |
| 15383316 | 2004 | hDKIR, a human homologue of the Drosophila kelch protein, involved in a ring-like structure. | 3 |
Citation
Dessen P
KLHL12 (kelch like family member 12)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64960/klhl12-(kelch-like-family-member-12)
