Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26249
MIM: 605775
HGNC: 6354
Ensembl: ENSG00000146021
Variants:
dbSNP: 26249
ClinVar: 26249
TCGA: ENSG00000146021
COSMIC: KLHL3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37481568 | 2023 | KLHL3-dependent WNK4 degradation affected by potassium through the neddylation and autophagy pathway. | 0 |
| 37481568 | 2023 | KLHL3-dependent WNK4 degradation affected by potassium through the neddylation and autophagy pathway. | 0 |
| 35585379 | 2022 | Kelch-like protein 3 in human disease and therapy. | 2 |
| 35585379 | 2022 | Kelch-like protein 3 in human disease and therapy. | 2 |
| 30718414 | 2019 | Calcineurin dephosphorylates Kelch-like 3, reversing phosphorylation by angiotensin II and regulating renal electrolyte handling. | 27 |
| 30931564 | 2019 | Unveiling the Distinct Mechanisms by which Disease-Causing Mutations in the Kelch Domain of KLHL3 Disrupt the Interaction with the Acidic Motif of WNK4 through Molecular Dynamics Simulation. | 3 |
| 31096542 | 2019 | KLHL3 single-nucleotide polymorphism is associated with essential hypertension in Chinese Han population. | 0 |
| 30718414 | 2019 | Calcineurin dephosphorylates Kelch-like 3, reversing phosphorylation by angiotensin II and regulating renal electrolyte handling. | 27 |
| 30931564 | 2019 | Unveiling the Distinct Mechanisms by which Disease-Causing Mutations in the Kelch Domain of KLHL3 Disrupt the Interaction with the Acidic Motif of WNK4 through Molecular Dynamics Simulation. | 3 |
| 31096542 | 2019 | KLHL3 single-nucleotide polymorphism is associated with essential hypertension in Chinese Han population. | 0 |
| 27727489 | 2017 | Phosphorylation of KLHL3 at serine 433 impairs its interaction with the acidic motif of WNK4: a molecular dynamics study. | 7 |
| 28222034 | 2017 | Three cases of Gordon syndrome with dominant KLHL3 mutations. | 5 |
| 28315668 | 2017 | cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases. | 4 |
| 28511177 | 2017 | Familial Hyperkalemia and Hypertension (FHHt) and KLHL3: Description of a Family with a New Recessive Mutation (S553L) Compared to a Family with a Dominant Mutation, Q309R, with Analysis of Urinary Sodium Chloride Cotransporter. | 6 |
| 27727489 | 2017 | Phosphorylation of KLHL3 at serine 433 impairs its interaction with the acidic motif of WNK4: a molecular dynamics study. | 7 |
Citation
Dessen P
KLHL3 (kelch like family member 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64972/new-content/cancer-prone-explorer/
