Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3850
MIM: 148043
HGNC: 6440
Ensembl: ENSG00000186442
Variants:
dbSNP: 3850
ClinVar: 3850
TCGA: ENSG00000186442
COSMIC: KRT3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186442 | ENST00000417996 | P12035 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33346999 | 2021 | Coexistence of Meesmann Corneal Dystrophy and a Pseudo-Unilateral Lattice Corneal Dystrophy in a Patient With a Novel Pathogenic Variant in the Keratin K3 Gene: A Case Report. | 2 |
| 33346999 | 2021 | Coexistence of Meesmann Corneal Dystrophy and a Pseudo-Unilateral Lattice Corneal Dystrophy in a Patient With a Novel Pathogenic Variant in the Keratin K3 Gene: A Case Report. | 2 |
| 29162348 | 2018 | Human aniridia limbal epithelial cells lack expression of keratins K3 and K12. | 7 |
| 29162348 | 2018 | Human aniridia limbal epithelial cells lack expression of keratins K3 and K12. | 7 |
| 26899008 | 2016 | PAX6 Isoforms, along with Reprogramming Factors, Differentially Regulate the Induction of Cornea-specific Genes. | 24 |
| 26899008 | 2016 | PAX6 Isoforms, along with Reprogramming Factors, Differentially Regulate the Induction of Cornea-specific Genes. | 24 |
| 23569037 | 2013 | Autosomal-dominant Meesmann epithelial corneal dystrophy without an exon mutation in the keratin-3 or keratin-12 gene in a Chinese family. | 1 |
| 23569037 | 2013 | Autosomal-dominant Meesmann epithelial corneal dystrophy without an exon mutation in the keratin-3 or keratin-12 gene in a Chinese family. | 1 |
| 18806880 | 2008 | Genetics of Meesmann corneal dystrophy: a novel mutation in the keratin 3 gene in an asymptomatic family suggests genotype-phenotype correlation. | 13 |
| 18806880 | 2008 | Genetics of Meesmann corneal dystrophy: a novel mutation in the keratin 3 gene in an asymptomatic family suggests genotype-phenotype correlation. | 13 |
| 16227835 | 2005 | Novel mutations in the helix termination motif of keratin 3 and keratin 12 in 2 Taiwanese families with Meesmann corneal dystrophy. | 8 |
| 16227835 | 2005 | Novel mutations in the helix termination motif of keratin 3 and keratin 12 in 2 Taiwanese families with Meesmann corneal dystrophy. | 8 |
Citation
Dessen P
KRT3 (keratin 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/65022/krt3-(keratin-3)
