Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 286887
MIM: 612315
HGNC: 20406
Ensembl: ENSG00000170465
Variants:
dbSNP: 286887
ClinVar: 286887
TCGA: ENSG00000170465
COSMIC: KRT6C
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000170465 | ENST00000252250 | P48668 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31768767 | 2020 | High expression of keratin 6C is associated with poor prognosis and accelerates cancer proliferation and migration by modulating epithelial-mesenchymal transition in lung adenocarcinoma. | 11 |
| 31768767 | 2020 | High expression of keratin 6C is associated with poor prognosis and accelerates cancer proliferation and migration by modulating epithelial-mesenchymal transition in lung adenocarcinoma. | 11 |
| 29357356 | 2018 | Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay. | 7 |
| 29357356 | 2018 | Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay. | 7 |
| 26301947 | 2016 | Focal PPK secondary to a novel KRT6C mutation (Pachyonychia congenita-K6c). | 1 |
| 26301947 | 2016 | Focal PPK secondary to a novel KRT6C mutation (Pachyonychia congenita-K6c). | 1 |
| 23662636 | 2013 | Collapse of the keratin filament network through the expression of mutant keratin 6c observed in a case of focal plantar keratoderma. | 1 |
| 23662636 | 2013 | Collapse of the keratin filament network through the expression of mutant keratin 6c observed in a case of focal plantar keratoderma. | 1 |
| 19609311 | 2010 | Keratin K6c mutations cause focal palmoplantar keratoderma. | 10 |
| 20081885 | 2010 | Mutations in a keratin 6 isomer (K6c) cause a type of focal palmoplantar keratoderma. | 6 |
| 19609311 | 2010 | Keratin K6c mutations cause focal palmoplantar keratoderma. | 10 |
| 20081885 | 2010 | Mutations in a keratin 6 isomer (K6c) cause a type of focal palmoplantar keratoderma. | 6 |
Citation
Dessen P
KRT6C (keratin 6C)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/65035/krt6c-(keratin-6c)
