Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 121391
MIM: 608248
HGNC: 28929
Ensembl: ENSG00000170484
Variants:
dbSNP: 121391
ClinVar: 121391
TCGA: ENSG00000170484
COSMIC: KRT74
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000170484 | ENST00000305620 | Q7RTS7 |
| ENSG00000170484 | ENST00000549343 | F8W1S1 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 24714551 | 2014 | Autosomal recessive transmission of a rare KRT74 variant causes hair and nail ectodermal dysplasia: allelism with dominant woolly hair/hypotrichosis. | 6 |
| 24714551 | 2014 | Autosomal recessive transmission of a rare KRT74 variant causes hair and nail ectodermal dysplasia: allelism with dominant woolly hair/hypotrichosis. | 6 |
| 21188418 | 2011 | Novel mutations in the keratin-74 (KRT74) gene underlie autosomal dominant woolly hair/hypotrichosis in Pakistani families. | 13 |
| 21188418 | 2011 | Novel mutations in the keratin-74 (KRT74) gene underlie autosomal dominant woolly hair/hypotrichosis in Pakistani families. | 13 |
| 20346438 | 2010 | Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture. | 26 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20346438 | 2010 | Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture. | 26 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19023099 | 2009 | Gene variants associated with ischemic stroke: the cardiovascular health study. | 20 |
| 19023099 | 2009 | Gene variants associated with ischemic stroke: the cardiovascular health study. | 20 |
| 17975119 | 2008 | Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. | 77 |
| 17975119 | 2008 | Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. | 77 |
| 12648212 | 2003 | K6irs1, K6irs2, K6irs3, and K6irs4 represent the inner-root-sheath-specific type II epithelial keratins of the human hair follicle. | 36 |
| 12648212 | 2003 | K6irs1, K6irs2, K6irs3, and K6irs4 represent the inner-root-sheath-specific type II epithelial keratins of the human hair follicle. | 36 |
Citation
Dessen P
KRT74 (keratin 74)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/65039/krt74-(keratin-74)
