Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3891
MIM: 602767
HGNC: 6462
Ensembl: ENSG00000135443
Variants:
dbSNP: 3891
ClinVar: 3891
TCGA: ENSG00000135443
COSMIC: KRT85
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000135443 | ENST00000257901 | P78386 |
| ENSG00000135443 | ENST00000544265 | F5GYI5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33605551 | 2021 | De novo filament formation by human hair keratins K85 and K35 follows a filament development pattern distinct from cytokeratin filament networks. | 1 |
| 33605551 | 2021 | De novo filament formation by human hair keratins K85 and K35 follows a filament development pattern distinct from cytokeratin filament networks. | 1 |
| 31273852 | 2019 | Compound heterozygosity for novel KRT85 variants associated with pure hair and nail ectodermal dysplasia. | 2 |
| 31273852 | 2019 | Compound heterozygosity for novel KRT85 variants associated with pure hair and nail ectodermal dysplasia. | 2 |
| 19865094 | 2010 | Mutations in the keratin 85 (KRT85/hHb5) gene underlie pure hair and nail ectodermal dysplasia. | 9 |
| 20409997 | 2010 | Autosomal recessive pure hair and nail ectodermal dysplasia linked to chromosome 12p11.1-q14.3 without KRTHB5 gene mutation. | 2 |
| 19865094 | 2010 | Mutations in the keratin 85 (KRT85/hHb5) gene underlie pure hair and nail ectodermal dysplasia. | 9 |
| 20409997 | 2010 | Autosomal recessive pure hair and nail ectodermal dysplasia linked to chromosome 12p11.1-q14.3 without KRTHB5 gene mutation. | 2 |
| 18021261 | 2008 | Transcriptional activation of a subset of hair keratin genes by the NF-kappaB effector p65/RelA. | 3 |
| 18021261 | 2008 | Transcriptional activation of a subset of hair keratin genes by the NF-kappaB effector p65/RelA. | 3 |
| 16525032 | 2006 | A mutation in the hair matrix and cuticle keratin KRTHB5 gene causes ectodermal dysplasia of hair and nail type. | 12 |
| 16525032 | 2006 | A mutation in the hair matrix and cuticle keratin KRTHB5 gene causes ectodermal dysplasia of hair and nail type. | 12 |
Citation
Dessen P
KRT85 (keratin 85)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/65047/krt85-(keratin-85)
