Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3904
MIM: 602993
HGNC: 6478
Ensembl: ENSG00000167618
Variants:
dbSNP: 3904
ClinVar: 3904
TCGA: ENSG00000167618
COSMIC: LAIR2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000167618 | ENST00000301202 | Q6ISS4 |
| ENSG00000167618 | ENST00000351841 | Q6ISS4 |
| ENSG00000167618 | ENST00000412608 | C9JFQ0 |
| ENSG00000167618 | ENST00000610651 | A0A087X1V4 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Adaptive Immune System | REACTOME | R-HSA-1280218 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | REACTOME | R-HSA-198933 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36593237 | 2023 | Association of LncRNA-PAX8-AS1 and LAIR-2 polymorphisms along with their expression with clinical and subclinical hypothyroidism. | 3 |
| 37422711 | 2023 | Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity. | 0 |
| 36593237 | 2023 | Association of LncRNA-PAX8-AS1 and LAIR-2 polymorphisms along with their expression with clinical and subclinical hypothyroidism. | 3 |
| 37422711 | 2023 | Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity. | 0 |
| 33841428 | 2021 | PNOC Expressed by B Cells in Cholangiocarcinoma Was Survival Related and LAIR2 Could Be a T Cell Exhaustion Biomarker in Tumor Microenvironment: Characterization of Immune Microenvironment Combining Single-Cell and Bulk Sequencing Technology. | 25 |
| 33841428 | 2021 | PNOC Expressed by B Cells in Cholangiocarcinoma Was Survival Related and LAIR2 Could Be a T Cell Exhaustion Biomarker in Tumor Microenvironment: Characterization of Immune Microenvironment Combining Single-Cell and Bulk Sequencing Technology. | 25 |
| 30216441 | 2019 | Screening the full leucocyte receptor complex genomic region revealed associations with pemphigus that might be explained by gene regulation. | 5 |
| 31548102 | 2019 | Human-specific LAIR2 contributes to the high invasiveness of human extravillous trophoblast cells. | 1 |
| 30216441 | 2019 | Screening the full leucocyte receptor complex genomic region revealed associations with pemphigus that might be explained by gene regulation. | 5 |
| 31548102 | 2019 | Human-specific LAIR2 contributes to the high invasiveness of human extravillous trophoblast cells. | 1 |
| 26721477 | 2016 | Differential gene expression levels might explain association of LAIR2 polymorphisms with pemphigus. | 10 |
| 26721477 | 2016 | Differential gene expression levels might explain association of LAIR2 polymorphisms with pemphigus. | 10 |
| 24192271 | 2014 | Inhibition of the classical and lectin pathway of the complement system by recombinant LAIR-2. | 14 |
| 24192271 | 2014 | Inhibition of the classical and lectin pathway of the complement system by recombinant LAIR-2. | 14 |
| 23332415 | 2013 | LAIR2-expressing extravillous trophoblasts associate with maternal spiral arterioles undergoing physiologic conversion. | 9 |
Citation
Dessen P
LAIR2 (leukocyte associated immunoglobulin like receptor 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/65161/lair2-(leukocyte-associated-immunoglobulin-like-receptor-2)
