Identity
HGNC
LOCATION
2p24.1
LOCUSID
ALIAS
HUMORF13,LAPTM4,MBNT,Mtrp
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9741
MIM: 618837
HGNC: 6924
Ensembl: ENSG00000068697
Variants:
dbSNP: 9741
ClinVar: 9741
TCGA: ENSG00000068697
COSMIC: LAPTM4A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000068697 | ENST00000175091 | Q15012 |
| ENSG00000068697 | ENST00000175091 | Q6IBP4 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Lysosome | KEGG | ko04142 |
| Lysosome | KEGG | hsa04142 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38588560 | 2024 | The role of hsa_circ_0042260/miR-4782-3p/LAPTM4A axis in gestational diabetes mellitus. | 0 |
| 38588560 | 2024 | The role of hsa_circ_0042260/miR-4782-3p/LAPTM4A axis in gestational diabetes mellitus. | 0 |
| 36675023 | 2023 | New Transcriptomic Biomarkers of 5-Fluorouracil Resistance. | 3 |
| 36675023 | 2023 | New Transcriptomic Biomarkers of 5-Fluorouracil Resistance. | 3 |
| 33836347 | 2021 | LAPTM4α is targeted from the Golgi to late endosomes/lysosomes in a manner dependent on the E3 ubiquitin ligase Nedd4-1 and ESCRT proteins. | 1 |
| 33836347 | 2021 | LAPTM4α is targeted from the Golgi to late endosomes/lysosomes in a manner dependent on the E3 ubiquitin ligase Nedd4-1 and ESCRT proteins. | 1 |
| 21553234 | 2011 | LAPTM4A interacts with hOCT2 and regulates its endocytotic recruitment. | 7 |
| 21553234 | 2011 | LAPTM4A interacts with hOCT2 and regulates its endocytotic recruitment. | 7 |
Citation
Dessen P
LAPTM4A (lysosomal protein transmembrane 4 alpha)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/65172/laptm4a-(lysosomal-protein-transmembrane-4-alpha)
