Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54900
HGNC: 26005
Ensembl: ENSG00000122188
Variants:
dbSNP: 54900
ClinVar: 54900
TCGA: ENSG00000122188
COSMIC: LAX1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000122188 | ENST00000367217 | Q8IWV1 |
| ENSG00000122188 | ENST00000442561 | Q8IWV1 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 24515439 | 2014 | Rab8 binding to immune cell-specific adaptor LAX facilitates formation of trans-Golgi network-proximal CTLA-4 vesicles for surface expression. | 19 |
| 24515439 | 2014 | Rab8 binding to immune cell-specific adaptor LAX facilitates formation of trans-Golgi network-proximal CTLA-4 vesicles for surface expression. | 19 |
| 22662118 | 2012 | The transmembrane region is responsible for targeting of adaptor protein LAX into "heavy rafts". | 3 |
| 22662118 | 2012 | The transmembrane region is responsible for targeting of adaptor protein LAX into "heavy rafts". | 3 |
| 19536175 | 2009 | Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. | 32 |
| 19536175 | 2009 | Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. | 32 |
| 18981125 | 2008 | Negative regulation of TCR signaling by linker for activation of X cells via phosphotyrosine-dependent and -independent mechanisms. | 7 |
| 18981125 | 2008 | Negative regulation of TCR signaling by linker for activation of X cells via phosphotyrosine-dependent and -independent mechanisms. | 7 |
| 12359715 | 2002 | Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling. | 33 |
| 12359715 | 2002 | Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling. | 33 |
| 12359715 | 2002 | Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling. | 33 |
| 12359715 | 2002 | Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling. | 33 |
Citation
Dessen P
LAX1 (lymphocyte transmembrane adaptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/65180/lax1-(lymphocyte-transmembrane-adaptor-1)
