ANXA2 (annexin A2)

2003-02-01  

Identity

HGNC
ANXA2
LOCATION
15q22.2
LOCUSID
302
ALIAS
ANX2,ANX2L4,CAL1H,HEL-S-270,LIP2,LPC2,LPC2D,P36,PAP-IV
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 302
MIM: 151740
HGNC: 537
Ensembl: ENSG00000182718

Variants:

dbSNP: 302
ClinVar: 302
TCGA: ENSG00000182718
COSMIC: ANXA2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182718ENST00000332680P07355
ENSG00000182718ENST00000396024P07355
ENSG00000182718ENST00000396024A0A024R5Z7
ENSG00000182718ENST00000421017P07355
ENSG00000182718ENST00000421017A0A024R5Z7
ENSG00000182718ENST00000451270P07355
ENSG00000182718ENST00000451270A0A024R5Z7
ENSG00000182718ENST00000557904H0YKV8
ENSG00000182718ENST00000557906H0YKS4
ENSG00000182718ENST00000558132H0YNP5
ENSG00000182718ENST00000558169H0YNB8
ENSG00000182718ENST00000558503H0YLV6
ENSG00000182718ENST00000558558H0YKX9
ENSG00000182718ENST00000558985H0YL33
ENSG00000182718ENST00000558986H0YMT9
ENSG00000182718ENST00000558998H0YNA0
ENSG00000182718ENST00000559113H0YN52
ENSG00000182718ENST00000559176H0YM50
ENSG00000182718ENST00000559350H0YMM1
ENSG00000182718ENST00000559370H0YMD9
ENSG00000182718ENST00000559467H0YKZ7
ENSG00000182718ENST00000559725H0YLE2
ENSG00000182718ENST00000559780H0YMW4
ENSG00000182718ENST00000559818H0YN42
ENSG00000182718ENST00000559956H0YKZ7
ENSG00000182718ENST00000560014H0YMU9
ENSG00000182718ENST00000560165H0YKS4
ENSG00000182718ENST00000560367H0YMD0
ENSG00000182718ENST00000560389H0YKS4
ENSG00000182718ENST00000560466H0YN28
ENSG00000182718ENST00000560468H0YKL9
ENSG00000182718ENST00000561022H0YKN4

Expression (GTEx)

0
500
1000
1500
2000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
HemostasisREACTOMER-HSA-109582
Dissolution of Fibrin ClotREACTOMER-HSA-75205
Muscle contractionREACTOMER-HSA-397014
Smooth Muscle ContractionREACTOMER-HSA-445355
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377824062024FGF19 promotes nasopharyngeal carcinoma progression by inducing angiogenesis via inhibiting TRIM21-mediated ANXA2 ubiquitination.0
379628082024Silencing AHNAK promotes nasopharyngeal carcinoma progression by upregulating the ANXA2 protein.1
381024612024Hsa_circ_0013561 promotes epithelial-mesenchymal transition and tumor progression by regulating ANXA2 via miR-23b-3p in ovarian cancer.1
381417692024LncNFYB promotes the proliferation of rheumatoid arthritis fibroblast-like synoviocytes via LncNFYB/ANXA2/ERK1/2 axis.0
382909722024ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.0
383170062024Stabilization of MOF (KAT8) by USP10 promotes esophageal squamous cell carcinoma proliferation and metastasis through epigenetic activation of ANXA2/Wnt signaling.1
384804772024FAXC interacts with ANXA2 and SRC in mitochondria and promotes tumorigenesis in cholangiocarcinoma.1
386054772024Nuclear autoantigenic sperm protein facilitates glioblastoma progression and radioresistance by regulating the ANXA2/STAT3 axis.0
377824062024FGF19 promotes nasopharyngeal carcinoma progression by inducing angiogenesis via inhibiting TRIM21-mediated ANXA2 ubiquitination.0
379628082024Silencing AHNAK promotes nasopharyngeal carcinoma progression by upregulating the ANXA2 protein.1
381024612024Hsa_circ_0013561 promotes epithelial-mesenchymal transition and tumor progression by regulating ANXA2 via miR-23b-3p in ovarian cancer.1
381417692024LncNFYB promotes the proliferation of rheumatoid arthritis fibroblast-like synoviocytes via LncNFYB/ANXA2/ERK1/2 axis.0
382909722024ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.0
383170062024Stabilization of MOF (KAT8) by USP10 promotes esophageal squamous cell carcinoma proliferation and metastasis through epigenetic activation of ANXA2/Wnt signaling.1
384804772024FAXC interacts with ANXA2 and SRC in mitochondria and promotes tumorigenesis in cholangiocarcinoma.1

Citation

Dessen P

ANXA2 (annexin A2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/655/anxa2-(annexin-a2)