ANXA7 (annexin A7)

2003-02-01  

Identity

HGNC
LOCATION
10q22.2
LOCUSID
ALIAS
ANX7,SNX,SYNEXIN
FUSION GENES

Other Information

Locus ID:

NCBI: 310
MIM: 186360
HGNC: 545
Ensembl: ENSG00000138279

Variants:

dbSNP: 310
ClinVar: 310
TCGA: ENSG00000138279
COSMIC: ANXA7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138279ENST00000372919P20073
ENSG00000138279ENST00000372921P20073
ENSG00000138279ENST00000394847B9ZVT2

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
118397552002Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation.90
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
248654242014Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression.29
196026872009Monosomy of chromosome 10 associated with dysregulation of epidermal growth factor signaling in glioblastomas.25
124454602002The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner.19
253393682015microRNA-155 promotes the proliferation of prostate cancer cells by targeting annexin 7.18
177085712007ANXA7 expression represents hormone-relevant tumor suppression in different cancers.14
119942952002Protein kinase C and guanosine triphosphate combine to potentiate calcium-dependent membrane fusion driven by annexin 7.9
236519242013Identification of a small molecule targeting annexin A7.8
184499142008The significance of ANXA7 expression and its correlation with poor cellular differentiation and enhanced metastatic potential of gastric cancer.7

Citation

Dessen P

ANXA7 (annexin A7)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/657/anxa7-(annexin-a7)