Identity
HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
EPM9,LAMB2,LMN2,MCPH27
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84823
MIM: 150341
HGNC: 6638
Ensembl: ENSG00000176619
Variants:
dbSNP: 84823
ClinVar: 84823
TCGA: ENSG00000176619
COSMIC: LMNB2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000176619 | ENST00000325327 | Q03252 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Apoptosis | KEGG | ko04210 |
| Apoptosis | KEGG | hsa04210 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37044185 | 2023 | The role of lamin B2 in human diseases. | 0 |
| 37044185 | 2023 | The role of lamin B2 in human diseases. | 0 |
| 35775376 | 2022 | Lamin B2 contributes to the proliferation of bladder cancer cells via activating the expression of cell division cycle‑associated protein 3. | 1 |
| 35775376 | 2022 | Lamin B2 contributes to the proliferation of bladder cancer cells via activating the expression of cell division cycle‑associated protein 3. | 1 |
| 33033404 | 2021 | Heterozygous lamin B1 and lamin B2 variants cause primary microcephaly and define a novel laminopathy. | 27 |
| 33782407 | 2021 | LMNB2 promotes the progression of colorectal cancer by silencing p21 expression. | 9 |
| 33033404 | 2021 | Heterozygous lamin B1 and lamin B2 variants cause primary microcephaly and define a novel laminopathy. | 27 |
| 33782407 | 2021 | LMNB2 promotes the progression of colorectal cancer by silencing p21 expression. | 9 |
| 32416090 | 2020 | Lamin B2 promotes the malignant phenotype of non-small cell lung cancer cells by upregulating dimethylation of histone 3 lysine 9. | 9 |
| 33211382 | 2020 | LMNB2 is a prognostic biomarker and correlated with immune infiltrates in hepatocellular carcinoma. | 8 |
| 32416090 | 2020 | Lamin B2 promotes the malignant phenotype of non-small cell lung cancer cells by upregulating dimethylation of histone 3 lysine 9. | 9 |
| 33211382 | 2020 | LMNB2 is a prognostic biomarker and correlated with immune infiltrates in hepatocellular carcinoma. | 8 |
| 26921073 | 2017 | Chromosomal aneuploidies induced upon Lamin B2 depletion are mislocalized in the interphase nucleus. | 20 |
| 26921073 | 2017 | Chromosomal aneuploidies induced upon Lamin B2 depletion are mislocalized in the interphase nucleus. | 20 |
| 25477337 | 2015 | Nuclear envelope remodelling during human spermiogenesis involves somatic B-type lamins and a spermatid-specific B3 lamin isoform. | 10 |
Citation
Dessen P
LMNB2 (lamin B2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/66141/
