AP3D1 (adaptor related protein complex 3 subunit delta 1)

2003-11-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
ADTD,HPS10,hBLVR
FUSION GENES

Other Information

Locus ID:

NCBI: 8943
MIM: 607246
HGNC: 568
Ensembl: ENSG00000065000

Variants:

dbSNP: 8943
ClinVar: 8943
TCGA: ENSG00000065000
COSMIC: AP3D1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000065000ENST00000345016O14617
ENSG00000065000ENST00000586370K7ERW8
ENSG00000065000ENST00000589369K7ELX8
ENSG00000065000ENST00000590683A0A087WYN6
ENSG00000065000ENST00000591284A0A2R8YCY8
ENSG00000065000ENST00000643010A0A2R8Y4J3
ENSG00000065000ENST00000643116O14617
ENSG00000065000ENST00000644728A0A2R8Y611

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
LysosomeKEGGko04142
LysosomeKEGGhsa04142

References

Pubmed IDYearTitleCitations
364454572023A homozygous AP3D1 missense variant in patients with sensorineural hearing loss as the leading manifestation.1
364454572023A homozygous AP3D1 missense variant in patients with sensorineural hearing loss as the leading manifestation.1
338869572021A BLOC-1-AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers.6
341666002021Connecting COPD GWAS Genes: FAM13A Controls TGFβ2 Secretion by Modulating AP-3 Transport.4
338869572021A BLOC-1-AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers.6
341666002021Connecting COPD GWAS Genes: FAM13A Controls TGFβ2 Secretion by Modulating AP-3 Transport.4
304724852019Biallelic mutations in AP3D1 cause Hermansky-Pudlak syndrome type 10 associated with immunodeficiency and seizure disorder.16
304724852019Biallelic mutations in AP3D1 cause Hermansky-Pudlak syndrome type 10 associated with immunodeficiency and seizure disorder.16
249166482015A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.25
249166482015A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.25
227059712012The HIV-1 matrix protein does not interact directly with the protein interactive domain of AP-3δ.6
227059712012The HIV-1 matrix protein does not interact directly with the protein interactive domain of AP-3δ.6
198512962010Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.7
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.17
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

AP3D1 (adaptor related protein complex 3 subunit delta 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/664/ap3d1-(adaptor-related-protein-complex-3-subunit-delta-1)