Identity
HGNC
LOCATION
11p15.4
LOCUSID
ALIAS
FE65,MGC:9072,RIR
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 322
MIM: 602709
HGNC: 581
Ensembl: ENSG00000166313
Variants:
dbSNP: 322
ClinVar: 322
TCGA: ENSG00000166313
COSMIC: APBB1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37918552 | 2023 | Alpha-secretase dependent nuclear localization of the amyloid-β precursor protein-binding protein Fe65 promotes DNA repair. | 0 |
| 37918552 | 2023 | Alpha-secretase dependent nuclear localization of the amyloid-β precursor protein-binding protein Fe65 promotes DNA repair. | 0 |
| 33047393 | 2020 | ARF6-Rac1 signaling-mediated neurite outgrowth is potentiated by the neuronal adaptor FE65 through orchestrating ARF6 and ELMO1. | 8 |
| 33123906 | 2020 | Aβ40 Promotes the Osteoblastic Differentiation of Aortic Valve Interstitial Cells through the RAGE Pathway. | 2 |
| 33047393 | 2020 | ARF6-Rac1 signaling-mediated neurite outgrowth is potentiated by the neuronal adaptor FE65 through orchestrating ARF6 and ELMO1. | 8 |
| 33123906 | 2020 | Aβ40 Promotes the Osteoblastic Differentiation of Aortic Valve Interstitial Cells through the RAGE Pathway. | 2 |
| 29615491 | 2018 | Neuronal adaptor FE65 stimulates Rac1-mediated neurite outgrowth by recruiting and activating ELMO1. | 13 |
| 29615491 | 2018 | Neuronal adaptor FE65 stimulates Rac1-mediated neurite outgrowth by recruiting and activating ELMO1. | 13 |
| 27836546 | 2017 | APBB1 reinforces cancer stem cell and epithelial-to-mesenchymal transition by regulating the IGF1R signaling pathway in non-small-cell lung cancer cells. | 9 |
| 28323844 | 2017 | Nuclear localization of amyloid-β precursor protein-binding protein Fe65 is dependent on regulated intramembrane proteolysis. | 5 |
| 28963516 | 2017 | Phosphorylation of FE65 at threonine 579 by GSK3β stimulates amyloid precursor protein processing. | 9 |
| 27836546 | 2017 | APBB1 reinforces cancer stem cell and epithelial-to-mesenchymal transition by regulating the IGF1R signaling pathway in non-small-cell lung cancer cells. | 9 |
| 28323844 | 2017 | Nuclear localization of amyloid-β precursor protein-binding protein Fe65 is dependent on regulated intramembrane proteolysis. | 5 |
| 28963516 | 2017 | Phosphorylation of FE65 at threonine 579 by GSK3β stimulates amyloid precursor protein processing. | 9 |
| 27176072 | 2016 | Fe65 Is Phosphorylated on Ser289 after UV-Induced DNA Damage. | 2 |
Citation
Dessen P
APBB1 (amyloid beta precursor protein binding family B member 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/665/apbb1-(amyloid-beta-precursor-protein-binding-family-b-member-1)
