BCL3 (BCL3 transcription coactivator)

2003-02-01

Identity

HGNC

BCL3

LOCATION

19q13.32

LOCUSID

602

ALIAS

BCL4,D19S37

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 602
MIM: 109560
HGNC: 998
Ensembl: ENSG00000069399

Variants:

dbSNP: 602
ClinVar: 602
TCGA: ENSG00000069399
COSMIC: BCL3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000069399	ENST00000164227	P20749
ENSG00000069399	ENST00000444487	H7C0A2

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
TNF signaling pathway	KEGG	hsa04668
TNF signaling pathway	KEGG	ko04668

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
31793036	2020	MicroRNA-627-5p inhibits the proliferation of hepatocellular carcinoma cells by targeting BCL3 transcription coactivator.	8
33544468	2021	PCAT1 induced by transcription factor YY1 promotes cholangiocarcinoma proliferation, migration and invasion by sponging miR-216a-3p to up-regulate oncogene BCL3.	6
33544468	2021	PCAT1 induced by transcription factor YY1 promotes cholangiocarcinoma proliferation, migration and invasion by sponging miR-216a-3p to up-regulate oncogene BCL3.	6
33819482	2021	Bcl3 Couples Cancer Stem Cell Enrichment With Pancreatic Cancer Molecular Subtypes.	4
33819482	2021	Bcl3 Couples Cancer Stem Cell Enrichment With Pancreatic Cancer Molecular Subtypes.	4
35355979	2022	Bcl-3: A Double-Edged Sword in Immune Cells and Inflammation.	12
35355979	2022	Bcl-3: A Double-Edged Sword in Immune Cells and Inflammation.	12
35641486	2022	Hepatocyte Bcl-3 protects from death-receptor mediated apoptosis and subsequent acute liver failure.	3
35641486	2022	Hepatocyte Bcl-3 protects from death-receptor mediated apoptosis and subsequent acute liver failure.	3
37132942	2023	Hsa_circ_0088036 promotes nonsmall cell lung cancer progression by regulating miR-1343-3p/Bcl-3 axis through TGFβ/Smad3/EMT signaling.	0

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Citation

Dessen P

BCL3 (BCL3 transcription coactivator)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/67/bcl3-(bcl3-transcription-coactivator)