API5 (apoptosis inhibitor 5)

2003-08-01  

Identity

HGNC
API5
LOCATION
11p12
LOCUSID
8539
ALIAS
AAC-11,AAC11
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8539
MIM: 609774
HGNC: 594
Ensembl: ENSG00000166181

Variants:

dbSNP: 8539
ClinVar: 8539
TCGA: ENSG00000166181
COSMIC: API5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166181ENST00000378852Q9BZZ5
ENSG00000166181ENST00000420461Q9BZZ5
ENSG00000166181ENST00000455725Q9BZZ5
ENSG00000166181ENST00000526394H0YER7
ENSG00000166181ENST00000531273Q9BZZ5
ENSG00000166181ENST00000534600G3V1C3
ENSG00000166181ENST00000534695E9PQK6

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
370954452023Altered expression of anti-apoptotic protein Api5 affects breast tumorigenesis.2
370954452023Altered expression of anti-apoptotic protein Api5 affects breast tumorigenesis.2
361987902022The γδ IEL effector API5 masks genetic susceptibility to Paneth cell death.14
361987902022The γδ IEL effector API5 masks genetic susceptibility to Paneth cell death.14
333196552021Evolution and Structure of API5 and Its Roles in Anti-Apoptosis.7
340769922021MicroRNA-224 modulates chemosensitivity of breast cancer cells to docetaxel by apoptosis inhibitor 5.0
343726972021DeSUMOylation of Apoptosis Inhibitor 5 by Avibirnavirus VP3 Supports Virus Replication.5
343855472021Interplay between p300 and HDAC1 regulate acetylation and stability of Api5 to regulate cell proliferation.4
333196552021Evolution and Structure of API5 and Its Roles in Anti-Apoptosis.7
340769922021MicroRNA-224 modulates chemosensitivity of breast cancer cells to docetaxel by apoptosis inhibitor 5.0
343726972021DeSUMOylation of Apoptosis Inhibitor 5 by Avibirnavirus VP3 Supports Virus Replication.5
343855472021Interplay between p300 and HDAC1 regulate acetylation and stability of Api5 to regulate cell proliferation.4
323837522020Regulation of mRNA export through API5 and nuclear FGF2 interaction.22
323837522020Regulation of mRNA export through API5 and nuclear FGF2 interaction.22
283367762017Apoptosis inhibitor 5 is an endogenous inhibitor of caspase-2.15

Citation

Dessen P

API5 (apoptosis inhibitor 5)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/675/api5-(apoptosis-inhibitor-5)