LPIN3 (lipin 3)

2014-11-01  

Identity

HGNC
LOCATION
20q12
LOCUSID
ALIAS
LIPN3L,SMP2,dJ620E11.2

Other Information

Locus ID:

NCBI: 64900
MIM: 605520
HGNC: 14451
Ensembl: ENSG00000132793

Variants:

dbSNP: 64900
ClinVar: 64900
TCGA: ENSG00000132793
COSMIC: LPIN3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132793ENST00000373257Q9BQK8
ENSG00000132793ENST00000445975H0Y5E1
ENSG00000132793ENST00000632009Q9BQK8

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Glycerolipid metabolismKEGGko00561
Glycerophospholipid metabolismKEGGko00564
Glycerolipid metabolismKEGGhsa00561
Glycerophospholipid metabolismKEGGhsa00564
Metabolic pathwaysKEGGhsa01100
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic ProphaseREACTOMER-HSA-68875
Nuclear Envelope BreakdownREACTOMER-HSA-2980766
Depolymerisation of the Nuclear LaminaREACTOMER-HSA-4419969
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Triglyceride BiosynthesisREACTOMER-HSA-75109
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Synthesis of PEREACTOMER-HSA-1483213
Synthesis of PCREACTOMER-HSA-1483191

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
377764352024Haploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and nucleocytoplasmic localization of Lipin1.2
377764352024Haploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and nucleocytoplasmic localization of Lipin1.2
335969342021Identification of lipidomic profiles associated with drug-resistant prostate cancer cells.11
335969342021Identification of lipidomic profiles associated with drug-resistant prostate cancer cells.11
224813842012Study of LPIN1, LPIN2 and LPIN3 in rhabdomyolysis and exercise-induced myalgia.36
232636582012Identification of a novel cell-penetrating peptide from human phosphatidate phosphatase LPIN3.13
224813842012Study of LPIN1, LPIN2 and LPIN3 in rhabdomyolysis and exercise-induced myalgia.36
232636582012Identification of a novel cell-penetrating peptide from human phosphatidate phosphatase LPIN3.13
207353592010Lipin proteins form homo- and hetero-oligomers.18
207353592010Lipin proteins form homo- and hetero-oligomers.18

Citation

Dessen P

LPIN3 (lipin 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68564/lpin3-(lipin-3)