LRRCC1 (leucine rich repeat and coiled-coil centrosomal protein 1)

2014-11-01  

Identity

HGNC
LRRCC1
LOCATION
8q21.2
LOCUSID
85444
ALIAS
CLERC,CLERK,SAP2,VFL1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 85444
MIM: 617791
HGNC: 29373
Ensembl: ENSG00000133739

Variants:

dbSNP: 85444
ClinVar: 85444
TCGA: ENSG00000133739
COSMIC: LRRCC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133739ENST00000360375Q9C099
ENSG00000133739ENST00000414626Q9C099
ENSG00000133739ENST00000517875E5RGA4
ENSG00000133739ENST00000522567E5RGA4
ENSG00000133739ENST00000522770E5RI08
ENSG00000133739ENST00000523669E5RGA4

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
353194622022Evolutionary conservation of centriole rotational asymmetry in the human centrosome.7
353194622022Evolutionary conservation of centriole rotational asymmetry in the human centrosome.7
187283982008An evolutionarily conserved leucine-rich repeat protein CLERC is a centrosomal protein required for spindle pole integrity.6
187283982008An evolutionarily conserved leucine-rich repeat protein CLERC is a centrosomal protein required for spindle pole integrity.6

Citation

Dessen P

LRRCC1 (leucine rich repeat and coiled-coil centrosomal protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68661/lrrcc1-(leucine-rich-repeat-and-coiled-coil-centrosomal-protein-1)