LRRTM2 (leucine rich repeat transmembrane neuronal 2)

2014-11-01  

Identity

HGNC
LOCATION
5q31.2
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 26045
MIM: 610868
HGNC: 19409
Ensembl: ENSG00000146006

Variants:

dbSNP: 26045
ClinVar: 26045
TCGA: ENSG00000146006
COSMIC: LRRTM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146006ENST00000274711O43300
ENSG00000146006ENST00000518785E5RIQ2
ENSG00000146006ENST00000521094E5RHE5

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Protein-protein interactions at synapsesREACTOMER-HSA-6794362
Interactions of neurexins and neuroligins at synapsesREACTOMER-HSA-6794361

References

Pubmed IDYearTitleCitations
302628342018Structural insights into modulation and selectivity of transsynaptic neurexin-LRRTM interaction.16
302628342018Structural insights into modulation and selectivity of transsynaptic neurexin-LRRTM interaction.16
217081312011Bidirectional transcription from human LRRTM2/CTNNA1 and LRRTM1/CTNNA2 gene loci leads to expression of N-terminally truncated CTNNA1 and CTNNA2 isoforms.5
217081312011Bidirectional transcription from human LRRTM2/CTNNA1 and LRRTM1/CTNNA2 gene loci leads to expression of N-terminally truncated CTNNA1 and CTNNA2 isoforms.5
192407912009Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis.26
192407912009Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis.26

Citation

Dessen P

LRRTM2 (leucine rich repeat transmembrane neuronal 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68672/lrrtm2-(leucine-rich-repeat-transmembrane-neuronal-2)