Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 347731
MIM: 610869
HGNC: 19410
Ensembl: ENSG00000198739
Variants:
dbSNP: 347731
ClinVar: 347731
TCGA: ENSG00000198739
COSMIC: LRRTM3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198739 | ENST00000361320 | Q86VH5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuronal System | REACTOME | R-HSA-112316 |
| Protein-protein interactions at synapses | REACTOME | R-HSA-6794362 |
| Interactions of neurexins and neuroligins at synapses | REACTOME | R-HSA-6794361 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 24463050 | 2014 | Association of LRRTM3 polymorphisms with late-onset Alzheimer's disease in Han Chinese. | 7 |
| 24463050 | 2014 | Association of LRRTM3 polymorphisms with late-onset Alzheimer's disease in Han Chinese. | 7 |
| 23750206 | 2013 | LRRTM3 interacts with APP and BACE1 and has variants associating with late-onset Alzheimer's disease (LOAD). | 9 |
| 23750206 | 2013 | LRRTM3 interacts with APP and BACE1 and has variants associating with late-onset Alzheimer's disease (LOAD). | 9 |
| 22393166 | 2012 | Effect of genetic variation in LRRTM3 on risk of Alzheimer disease. | 12 |
| 22710909 | 2012 | LRRTM3 is dispensable for amyloid-β production in mice. | 0 |
| 22393166 | 2012 | Effect of genetic variation in LRRTM3 on risk of Alzheimer disease. | 12 |
| 22710909 | 2012 | LRRTM3 is dispensable for amyloid-β production in mice. | 0 |
| 21598020 | 2011 | Alpha T-catenin (CTNNA3): a gene in the hand is worth two in the nest. | 8 |
| 21598020 | 2011 | Alpha T-catenin (CTNNA3): a gene in the hand is worth two in the nest. | 8 |
| 20678249 | 2010 | Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry. | 25 |
| 20678249 | 2010 | Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry. | 25 |
| 19105203 | 2009 | An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3. | 18 |
| 19105203 | 2009 | An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3. | 18 |
| 19105203 | 2009 | An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3. | 18 |
Citation
Dessen P
LRRTM3 (leucine rich repeat transmembrane neuronal 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/68673/lrrtm3-(leucine-rich-repeat-transmembrane-neuronal-3)
