LUC7L3 (LUC7 like 3 pre-mRNA splicing factor)

2014-11-01  

Identity

HGNC
LUC7L3
LOCATION
17q21.33
LOCUSID
51747
ALIAS
CRA,CREAP-1,CROP,LUC7A,OA48-18,hLuc7A
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51747
MIM: 609434
HGNC: 24309
Ensembl: ENSG00000108848

Variants:

dbSNP: 51747
ClinVar: 51747
TCGA: ENSG00000108848
COSMIC: LUC7L3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108848ENST00000240304O95232
ENSG00000108848ENST00000393227J3KPP4
ENSG00000108848ENST00000503728H0YBV7
ENSG00000108848ENST00000504065H0YA81
ENSG00000108848ENST00000504563C9JL41
ENSG00000108848ENST00000505619D6RDI2
ENSG00000108848ENST00000505658O95232
ENSG00000108848ENST00000506686C9JL41
ENSG00000108848ENST00000507200H7C5U7
ENSG00000108848ENST00000508045C9JL41
ENSG00000108848ENST00000508482E7EN55
ENSG00000108848ENST00000509335C9JL41
ENSG00000108848ENST00000509487H0YAY6
ENSG00000108848ENST00000510984D6RHH0
ENSG00000108848ENST00000511974H0YAX1
ENSG00000108848ENST00000513025U3KQT3
ENSG00000108848ENST00000513969H0YAR4
ENSG00000108848ENST00000625349C9JL41

Expression (GTEx)

0
50
100
150
200
250
300
350
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
338528592021Functional analyses of human LUC7-like proteins involved in splicing regulation and myeloid neoplasms.15
338528592021Functional analyses of human LUC7-like proteins involved in splicing regulation and myeloid neoplasms.15
295128562018Analysis of psoriasis-relevant gene expression and exon usage alterations after silencing of SR-rich splicing regulators.5
295128562018Analysis of psoriasis-relevant gene expression and exon usage alterations after silencing of SR-rich splicing regulators.5
285893702017Splicing factors differentially expressed in psoriasis alter mRNA maturation of disease-associated EDA+ fibronectin.8
285893702017Splicing factors differentially expressed in psoriasis alter mRNA maturation of disease-associated EDA+ fibronectin.8
278571582016LUC7L3/CROP inhibits replication of hepatitis B virus via suppressing enhancer II/basal core promoter activity.13
278571582016LUC7L3/CROP inhibits replication of hepatitis B virus via suppressing enhancer II/basal core promoter activity.13
229398792013RBM25/LUC7L3 function in cardiac sodium channel splicing regulation of human heart failure.19
229398792013RBM25/LUC7L3 function in cardiac sodium channel splicing regulation of human heart failure.19
218599732011Role of RBM25/LUC7L3 in abnormal cardiac sodium channel splicing regulation in human heart failure.47
218599732011Role of RBM25/LUC7L3 in abnormal cardiac sodium channel splicing regulation in human heart failure.47
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37
206770142010An approach based on a genome-wide association study reveals candidate loci for narcolepsy.19
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37

Citation

Dessen P

LUC7L3 (LUC7 like 3 pre-mRNA splicing factor)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68699/luc7l3-(luc7-like-3-pre-mrna-splicing-factor)