Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 127018
MIM: 616548
HGNC: 20440
Ensembl: ENSG00000143353
Variants:
dbSNP: 127018
ClinVar: 127018
TCGA: ENSG00000143353
COSMIC: LYPLAL1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000143353 | ENST00000366927 | Q5VWZ2 |
| ENSG00000143353 | ENST00000366928 | Q5VWZ2 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37676718 | 2023 | ELAVL4 promotes the tumorigenesis of small cell lung cancer by stabilizing LncRNA LYPLAL1-DT and enhancing profilin 2 activation. | 1 |
| 37802025 | 2023 | Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy. | 2 |
| 37676718 | 2023 | ELAVL4 promotes the tumorigenesis of small cell lung cancer by stabilizing LncRNA LYPLAL1-DT and enhancing profilin 2 activation. | 1 |
| 37802025 | 2023 | Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy. | 2 |
| 29648650 | 2018 | NAFLD risk alleles in PNPLA3, TM6SF2, GCKR and LYPLAL1 show divergent metabolic effects. | 64 |
| 29648650 | 2018 | NAFLD risk alleles in PNPLA3, TM6SF2, GCKR and LYPLAL1 show divergent metabolic effects. | 64 |
| 28645872 | 2017 | Two obesity susceptibility loci in LYPLAL1 and ETV5 independently associated with childhood hypertension in Chinese population. | 2 |
| 28645872 | 2017 | Two obesity susceptibility loci in LYPLAL1 and ETV5 independently associated with childhood hypertension in Chinese population. | 2 |
| 26848030 | 2016 | Effects of Obesity Related Genetic Variations on Visceral and Subcutaneous Fat Distribution in a Chinese Population. | 22 |
| 27181159 | 2016 | A genetic variant in proximity to the gene LYPLAL1 is associated with lower hunger feelings and increased weight loss following Roux-en-Y gastric bypass surgery. | 4 |
| 27752939 | 2016 | Association between PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), GCKR (rs780094), and elevated transaminase levels in overweight/obese Mexican adults. | 13 |
| 26848030 | 2016 | Effects of Obesity Related Genetic Variations on Visceral and Subcutaneous Fat Distribution in a Chinese Population. | 22 |
| 27181159 | 2016 | A genetic variant in proximity to the gene LYPLAL1 is associated with lower hunger feelings and increased weight loss following Roux-en-Y gastric bypass surgery. | 4 |
| 27752939 | 2016 | Association between PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), GCKR (rs780094), and elevated transaminase levels in overweight/obese Mexican adults. | 13 |
| 23221025 | 2013 | Replication study of 15 recently published Loci for body fat distribution in the Japanese population. | 6 |
Citation
Dessen P
LYPLAL1 (lysophospholipase like 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/68724/lyplal1-(lysophospholipase-like-1)
