LYRM7 (LYR motif containing 7)

2014-11-01  

Identity

HGNC
LOCATION
5q23.3
LOCUSID
ALIAS
C5orf31,MC3DN8,MZM1L

Other Information

Locus ID:

NCBI: 90624
MIM: 615831
HGNC: 28072
Ensembl: ENSG00000186687

Variants:

dbSNP: 90624
ClinVar: 90624
TCGA: ENSG00000186687
COSMIC: LYRM7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186687ENST00000379380Q5U5X0
ENSG00000186687ENST00000507584D6RBV5
ENSG00000186687ENST00000510516D6R994

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381047422024TNF-α induced NF-κB mediated LYRM7 expression modulates the tumor growth and metastatic ability in breast cancer.1
381047422024TNF-α induced NF-κB mediated LYRM7 expression modulates the tumor growth and metastatic ability in breast cancer.1
286941942017LYRM7 - associated complex III deficiency: A clinical, molecular genetic, MR tomographic, and biochemical study.8
286941942017LYRM7 - associated complex III deficiency: A clinical, molecular genetic, MR tomographic, and biochemical study.8
269126322016LYRM7 mutations cause a multifocal cavitating leukoencephalopathy with distinct MRI appearance.16
269126322016LYRM7 mutations cause a multifocal cavitating leukoencephalopathy with distinct MRI appearance.16
240143942013A homozygous mutation in LYRM7/MZM1L associated with early onset encephalopathy, lactic acidosis, and severe reduction of mitochondrial complex III activity.30
240143942013A homozygous mutation in LYRM7/MZM1L associated with early onset encephalopathy, lactic acidosis, and severe reduction of mitochondrial complex III activity.30
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.94
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.94

Citation

Dessen P

LYRM7 (LYR motif containing 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68730/lyrm7-(lyr-motif-containing-7)