Identity
HGNC
LOCATION
5q13.2
LOCUSID
ALIAS
MCCB,MCCCbeta
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64087
MIM: 609014
HGNC: 6937
Ensembl: ENSG00000131844
Variants:
dbSNP: 64087
ClinVar: 64087
TCGA: ENSG00000131844
COSMIC: MCCC2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38783226 | 2024 | ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis. | 0 |
| 38783226 | 2024 | ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis. | 0 |
| 37828426 | 2023 | MCCC2 is a novel mediator between mitochondria and telomere and functions as an oncogene in colorectal cancer. | 3 |
| 37828426 | 2023 | MCCC2 is a novel mediator between mitochondria and telomere and functions as an oncogene in colorectal cancer. | 3 |
| 33423264 | 2021 | [Analysis of MCCC2 gene variant in a pedigree affected with 3-methylcrotonyl coenzyme A carboxylase deficiency]. | 0 |
| 33423264 | 2021 | [Analysis of MCCC2 gene variant in a pedigree affected with 3-methylcrotonyl coenzyme A carboxylase deficiency]. | 0 |
| 32205097 | 2020 | MCCC2 overexpression predicts poorer prognosis and promotes cell proliferation in colorectal cancer. | 7 |
| 32205097 | 2020 | MCCC2 overexpression predicts poorer prognosis and promotes cell proliferation in colorectal cancer. | 7 |
| 30895811 | 2019 | Methylcrotonoyl-CoA carboxylase 2 overexpression predicts an unfavorable prognosis and promotes cell proliferation in breast cancer. | 10 |
| 31901042 | 2019 | [Genetic analysis of newborns with abnormal metabolism of 3-hydroxyisovalerylcarnitine]. | 0 |
| 30895811 | 2019 | Methylcrotonoyl-CoA carboxylase 2 overexpression predicts an unfavorable prognosis and promotes cell proliferation in breast cancer. | 10 |
| 31901042 | 2019 | [Genetic analysis of newborns with abnormal metabolism of 3-hydroxyisovalerylcarnitine]. | 0 |
| 27601257 | 2016 | 3-Methylcrotonyl-CoA carboxylase deficiency: Mutational spectrum derived from comprehensive newborn screening. | 8 |
| 27601257 | 2016 | 3-Methylcrotonyl-CoA carboxylase deficiency: Mutational spectrum derived from comprehensive newborn screening. | 8 |
| 25382614 | 2015 | Identification of eight novel mutations and transcript analysis of two splicing mutations in Chinese newborns with MCC deficiency. | 7 |
Citation
Dessen P
MCCC2 (methylcrotonyl-CoA carboxylase subunit 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/68840/mccc2-(methylcrotonyl-coa-carboxylase-subunit-2)
