MED20 (mediator complex subunit 20)

2014-11-01  

Identity

HGNC
MED20
LOCATION
6p21.1
LOCUSID
9477
ALIAS
PRO0213,SRB2,TRFP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9477
MIM: 612915
HGNC: 16840
Ensembl: ENSG00000124641

Variants:

dbSNP: 9477
ClinVar: 9477
TCGA: ENSG00000124641
COSMIC: MED20

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124641ENST00000265350Q9H944
ENSG00000124641ENST00000394251A6PVP4
ENSG00000124641ENST00000409060B7ZBQ3
ENSG00000124641ENST00000409312Q9H944
ENSG00000124641ENST00000434077B7ZBQ1

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)REACTOMER-HSA-400206
PPARA activates gene expressionREACTOMER-HSA-1989781
Developmental BiologyREACTOMER-HSA-1266738
Transcriptional regulation of white adipocyte differentiationREACTOMER-HSA-381340

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
289471012017All three human scavenger receptor class B proteins can bind and transport all three macular xanthophyll carotenoids.26
289471012017All three human scavenger receptor class B proteins can bind and transport all three macular xanthophyll carotenoids.26
254464062015MED20 mutation associated with infantile basal ganglia degeneration and brain atrophy.5
254464062015MED20 mutation associated with infantile basal ganglia degeneration and brain atrophy.5

Citation

Dessen P

MED20 (mediator complex subunit 20)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68876/med20-(mediator-complex-subunit-20)