ARCN1 (archain 1)

2003-06-01  

Identity

HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
COPD,SRMMD
FUSION GENES

Other Information

Locus ID:

NCBI: 372
MIM: 600820
HGNC: 649
Ensembl: ENSG00000095139

Variants:

dbSNP: 372
ClinVar: 372
TCGA: ENSG00000095139
COSMIC: ARCN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000095139ENST00000264028P48444
ENSG00000095139ENST00000264028B0YIW5
ENSG00000095139ENST00000359415B0YIW6
ENSG00000095139ENST00000392859P48444
ENSG00000095139ENST00000534182E9PK34
ENSG00000095139ENST00000614498Q6P1Q5

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
COPI-mediated anterograde transportREACTOMER-HSA-6807878
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-dependent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811434

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
274766552016ARCN1 Mutations Cause a Recognizable Craniofacial Syndrome Due to COPI-Mediated Transport Defects.14
264987662016MicroRNA-33a disturbs influenza A virus replication by targeting ARCN1 and inhibiting viral ribonucleoprotein activity.12
233007982012Fine mapping of a region of chromosome 11q23.3 reveals independent locus associated with risk of glioma.6
227508762012Crystallization and preliminary X-ray analysis of the C-terminal domain of δ-COP, a medium-sized subunit of the COPI complex involved in membrane trafficking.0

Citation

Dessen P

ARCN1 (archain 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/689/arcn1-(archain-1)