MEPCE (methylphosphate capping enzyme)

2014-11-01  

Identity

HGNC
LOCATION
7q22.1
LOCUSID
ALIAS
BCDIN3
FUSION GENES

Other Information

Locus ID:

NCBI: 56257
MIM: 611478
HGNC: 20247
Ensembl: ENSG00000146834

Variants:

dbSNP: 56257
ClinVar: 56257
TCGA: ENSG00000146834
COSMIC: MEPCE

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146834ENST00000310512Q7L2J0
ENSG00000146834ENST00000414441Q7L2J0

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
369286612023Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.2
369286612023Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.2
334161482021Long non‑coding RNA ST8SIA6‑AS1 promotes the migration and invasion of hypoxia‑treated hepatocellular carcinoma cells through the miR‑338/MEPCE axis.9
334161482021Long non‑coding RNA ST8SIA6‑AS1 promotes the migration and invasion of hypoxia‑treated hepatocellular carcinoma cells through the miR‑338/MEPCE axis.9
315908912019HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb.2
315908912019HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb.2
294254942018Crosstalk between the RNA Methylation and Histone-Binding Activities of MePCE Regulates P-TEFb Activation on Chromatin.17
294254942018Crosstalk between the RNA Methylation and Histone-Binding Activities of MePCE Regulates P-TEFb Activation on Chromatin.17
282548382017The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression.22
282548382017The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression.22
258632852015Intermolecular recognition of the non-coding RNA 7SK and HEXIM protein in perspective.11
258632852015Intermolecular recognition of the non-coding RNA 7SK and HEXIM protein in perspective.11
179781742007Human capping enzyme promotes formation of transcriptional R loops in vitro.20
179781742007Human capping enzyme promotes formation of transcriptional R loops in vitro.20

Citation

Dessen P

MEPCE (methylphosphate capping enzyme)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68904/mepce-(methylphosphate-capping-enzyme)